産官学連携推進センター - 藤田医科大学教育・研究業績

研究キーワード

婦人科.腫瘍.エピジェネティクス.マイクロRNA

研究分野

ライフサイエンス / 産婦人科学 /

経歴

2009年

- 東北大学大学院医学系研究科医科学助教

東北大学大学院医学系研究科医科学専攻発生・発達医学講座婦人科学分野助教

学歴

-

2009年

東北大学医学系研究科

-

2009年

東北大学

-

2003年

北里大学獣医畜産学部動物資源科学科

-

2003年

北里大学

MISC

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Expression of steroid and xenobiotic receptor in uterine carcinosarcoma, leiomyosarcoma and endometrial stromal sarcoma

Xiaoni Yue Hiroki Utsunomiya Jun-Ichi Akahira Fumihiko Suzuki Kiyoshi Ito Satoru Nagase Hironobu Sasano Nobuo Yaegashi

ONCOLOGY LETTERS 5(3) 835-839 2013年3月

We analyzed the expression of the steroid and xenobiotic receptor (SXR) in human uterine sarcomas and evaluated its clinical significance. Forty-seven cases with archival specimens were examined for SXR expression using immunohistochemistry. All c...

MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma

Eri Hiroki Fumihiko Suzuki Jun-ichi Akahira Satoru Nagase Kiyoshi Ito Jun-ichi Sugawara Yasuhiro Miki Takashi Suzuki Hironobu Sasano Nobuo Yaegashi

INTERNATIONAL JOURNAL OF CANCER 131(4) E395-E404 2012年8月

Endometrial serous adenocarcinoma (ESC) is aggressive and carries a poor prognosis. p53 is frequently mutated in ESC. microRNAs (miRNAs) are a direct p53 target and have been implicated in cancer cell behavior. In this study, we compared miRNA exp...

MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma

Eri Hiroki Fumihiko Suzuki Jun-ichi Akahira Satoru Nagase Kiyoshi Ito Jun-ichi Sugawara Yasuhiro Miki Takashi Suzuki Hironobu Sasano Nobuo Yaegashi

INTERNATIONAL JOURNAL OF CANCER 131(4) E395-E404 2012年8月

Endometrial serous adenocarcinoma (ESC) is aggressive and carries a poor prognosis. p53 is frequently mutated in ESC. microRNAs (miRNAs) are a direct p53 target and have been implicated in cancer cell behavior. In this study, we compared miRNA exp...

High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method

Hitoshi Hiura Hiroaki Okae Hisato Kobayash Naoko Miyauchi Fumi Sato Akiko Sato Fumihiko Suzuki Satoru Nagase Junichi Sugawara Kunihiko Nakai Nobuo Yaegashi Takahiro Arima

BMC MEDICAL GENOMICS 5 8-17 2012年3月

Background: Aberrant DNA methylation leads to loss of heterozygosity (LOH) or loss of imprinting (LOI) as the first hit during human carcinogenesis. Recently we developed a new high-throughput, high-resolution DNA methylation analysis method, bisu...

High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method

Hitoshi Hiura Hiroaki Okae Hisato Kobayash Naoko Miyauchi Fumi Sato Akiko Sato Fumihiko Suzuki Satoru Nagase Junichi Sugawara Kunihiko Nakai Nobuo Yaegashi Takahiro Arima

BMC MEDICAL GENOMICS 5 8-17 2012年3月

Background: Aberrant DNA methylation leads to loss of heterozygosity (LOH) or loss of imprinting (LOI) as the first hit during human carcinogenesis. Recently we developed a new high-throughput, high-resolution DNA methylation analysis method, bisu...