産官学連携推進センター - 藤田医科大学教育・研究業績

研究キーワード

婦人科.腫瘍.エピジェネティクス.マイクロRNA

研究分野

ライフサイエンス / 産婦人科学 /

経歴

2009年

- 東北大学大学院医学系研究科医科学助教

東北大学大学院医学系研究科医科学専攻発生・発達医学講座婦人科学分野助教

学歴

-

2009年

東北大学医学系研究科

-

2009年

東北大学

-

2003年

北里大学獣医畜産学部動物資源科学科

-

2003年

北里大学

MISC

<1 2 345 >

DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm

Hisato Kobayashi Hitoshi Hiura Rosalind M. John Akiko Sato Eiko Otsu Naoko Kobayashi Rei Suzuki Fumihiko Suzuki Chika Hayashi Takafumi Utsunomiya Nobuo Yaegashi Takahiro Arima

EUROPEAN JOURNAL OF HUMAN GENETICS 17(12) 1582-1591 2009年12月

There is an increased prevalence of imprinting disorders, such as Beckwith-Wiedemann syndrome, associated with human assisted reproductive technologies (ART). Work on animal models suggests that in vitro culture may be the source of these imprinti...

Loss of estrogen receptor β isoform expression and its correlation with aberrant DNA methylation of the 5'-untranslated region in human epithelial ovarian carcinoma.

Fumihiko Suzuki Jun-ichi Akahira Ikumi Miura Takashi Suzuki Kiyoshi Ito Shin-ichi Hayashi Hironobu Sasano Nobuo Yaegashi

Cancer Science 99(12) 2365-2372 2008年12月

Loss of estrogen receptor beta isoform expression and its correlation with aberrant DNA methylation of the 5'-untranslated region in human epithelial ovarian carcinoma

Fumihiko Suzuki Jun-ichi Akahira Ikumi Miura Takashi Suzuki Kiyoshi Ito Shin-ichi Hayashi Hironobu Sasano Nobuo Yaegashi

CANCER SCIENCE 99(12) 2365-2372 2008年12月

Evidence exists that sex steroids such as estrogens affect epithelial ovarian cancer. The expression profiles of the estrogen receptors (ER) and ER beta in particular have not been fully described. Therefore, in our present study, we examined the ...

Decreased expression of RIZ1 and its clinicopathological significance in epithelial ovarian carcinoma: Correlation with epigenetic inactivation by aberrant DNA methylation

Jun-ichi Akahira Fumihiko Suzuki Takashi Suzuki Ikumi Miura Noriko Kamogawa Yasuhiro Miki Kiyoshi Ito Nobuo Yaegashi Hironobu Sasano

PATHOLOGY INTERNATIONAL 57(11) 725-733 2007年11月

The retinoblastoma protein-interacting zinc finger gene (RIZ1) is considered a tumor suppressor gene. The purpose of the present study was to examine the expression of RIZ1 and evaluate its clinicopathological significance in ovarian carcinoma. Im...

Decreased expression of RIZ1 and its clinicopathological significance in epithelial ovarian carcinoma: Correlation with epigenetic inactivation by aberrant DNA methylation

Jun-ichi Akahira Fumihiko Suzuki Takashi Suzuki Ikumi Miura Noriko Kamogawa Yasuhiro Miki Kiyoshi Ito Nobuo Yaegashi Hironobu Sasano

PATHOLOGY INTERNATIONAL 57(11) 725-733 2007年11月

The retinoblastoma protein-interacting zinc finger gene (RIZ1) is considered a tumor suppressor gene. The purpose of the present study was to examine the expression of RIZ1 and evaluate its clinicopathological significance in ovarian carcinoma. Im...