医学部

研究分野

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ライフサイエンス / 栄養学、健康科学 /
ライフサイエンス / 衛生学、公衆衛生学分野：実験系を含まない /
ライフサイエンス / 衛生学、公衆衛生学分野：実験系を含む /
ライフサイエンス / 医療管理学、医療系社会学 /
ライフサイエンス / 代謝、内分泌学 /

受賞

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2010年

大阪大学大学院医学系研究科保健学専攻優秀論文賞
山田宏哉

日本臨床検査医学会, 若手研究奨励賞
山田宏哉

第56日本甲状腺学会コスミック・研究創成賞優秀賞
山田宏哉

予防医学研究海外研修奨学助成金：甕哲司賞
山田宏哉

第53回日本甲状腺学会若手奨励賞
山田宏哉

論文

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Association of drinking behaviors with TXNIP DNA methylation levels in leukocytes among the general Japanese population.

Keisuke Maeda Hiroya Yamada Eiji Munetsuna Ryosuke Fujii Mirai Yamazaki Yoshitaka Ando Genki Mizuno Hiroaki Ishikawa Koji Ohashi Yoshiki Tsuboi Yuji Hattori Yuya Ishihara Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

The American journal of drug and alcohol abuse 48(3) 1-9 2022年4月

Background: Thioredoxin-interacting protein (TXNIP) controls the cellular redox balance by binding to and inhibiting the expression and function of thioredoxin. DNA methylation of the TXNIP gene is involved in the regulation of TXNIP mRNA expressi...

Increased brain-derived neurotrophic factor in the serum of persons with nonalcoholic fatty liver disease.

Yuji Hattori Hiroya Yamada Eiji Munetsuna Yoshitaka Ando Genki Mizuno Ryosuke Fujii Yoshiki Tsuboi Naohiro Ichino Keisuke Osakabe Keiko Sugimoto Hiroaki Ishikawa Koji Ohashi Koji Suzuki

Endocrine journal 69(8) 999-1006 2022年3月

The increasing prevalence of nonalcoholic fatty liver disease (NAFLD) is a global health problem. In recent years, the inhibitory effect of brain-derived neurotrophic factor (BDNF) on diabetes mellitus and fatty liver has been clarified. The purpo...

DNA methylation level of the gene encoding thioredoxin-interacting protein in peripheral blood cells is associated with metabolic syndrome in the Japanese general population.

Mirai Yamazaki Hiroya Yamada Eiji Munetsuna Keisuke Maeda Yoshitaka Ando Genki Mizuno Ryosuke Fujii Yoshiki Tsuboi Koji Ohashi Hiroaki Ishikawa Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

Endocrine journal 69(3) 319-326 2022年3月

Metabolic syndrome (MetS) is cluster of metabolic diseases, including abdominal obesity, hyperglycemia, high blood pressure, and dyslipidemia, that directly escalate the risk of type 2 diabetes, heart disease, and stroke. Thioredoxin-interacting p...

Investigation of miRNA expression profiles using cohort samples reveals potential early detectability of colorectal cancers by serum miR-26a-5p before clinical diagnosis.

Asahi Hishida Hiroya Yamada Yoshitaka Ando Yoshinaga Okugawa Manabu Shiozawa Yohei Miyagi Yataro Daigo Yuji Toiyama Yumiko Shirai Koji Tanaka Yoko Kubo Rieko Okada Mako Nagayoshi Takashi Tamura Atsuyoshi Mori Takaaki Kondo Nobuyuki Hamajima Kenji Takeuchi Kenji Wakai

Oncology letters 23(3) 87-87 2022年3月

Previous studies have investigated the usefulness of microRNA (miRNA/miR) expression data for the early detection of colorectal cancer (CRC). However, limited data are available regarding miRNAs that detect CRC before clinical diagnoses. According...

DNA methylation is associated with muscle loss in community-dwelling older men -the Yakumo study- : a preliminary experimental study.

Daisaku Kato Yasuhiko Takegami Taisuke Seki Hiroaki Nakashima Yusuke Osawa Koji Suzuki Hiroya Yamada Yukiharu Hasegawa Shiro Imagama

Nagoya journal of medical science 84(1) 60-68 2022年2月

Frailty is a state of reduced muscle strength and activity in older people. DNA methylation is associated with osteoporosis and muscle loss in murine and other animal studies, but there are no epidemiological studies in humans. This study aimed to...