The journals of gerontology. Series A, Biological sciences and medical sciences 77(6) 1150-1158 2022年1月
Aging is important medical and social problem. Excessive angiopoietin-like protein (ANGPTL)-2 signaling causes chronic tissue inflammation, promoting development and progression of aging-related diseases. Moreover, circulating ANGPTL2 levels repor...
Consumption of fructose-containing beverages such as high-fructose corn syrup (HFCS) is increasing, raising concerns about the negative effects of excessive fructose intake. A recent report indicated that excess HFCS intake impairs hippocampal fun...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35(12) e22030 2021年12月
Given that fructose consumption has increased by more than 10-fold in recent decades, it is possible that excess maternal fructose consumption causes harmful effects in the next generation. This study attempted to elucidate the mechanism of the ha...
Clinica chimica acta; international journal of clinical chemistry 521 97-103 2021年10月
BACKGROUND: Although a number of microRNAs (miRNA) reflecting kidney function has been identified, prospective studies are now urgently needed to determine a clinical utility of these miRNAs among general populations. The purpose of this study was...
Journal of epidemiology and community health 75(9) 890-895 2021年9月
BACKGROUND: DNA methylation plays an important role in the pathogenesis and progression of cardiovascular disease (CVD) but the prospective association of DNA methylation with CVD has not been evaluated. Here, we conducted a prospective study to e...