BRIEF BIOGRAPHY: While Prof. Dr. Yukio Ozaki is an interventional cardiologist having specialty in the field of acute myocardial infarction (Ozaki Y. et al; CVIT expert consensus document on primary PCI for AMI in 2018. Cardiovasc Interv Ther. 2018;33:178-203), coronary imaging such as OCT, IVUS, NIRS, angioscopy, CT angiography as well as structural heart disease (SHD). While Dr. Yukio Ozaki is the first Japanese fellow under the supervision of Prof. Patrick W. Serruys in the Thoraxcenter Erasmus University Rotterdam, he defended his thesis entitled “Clinical Application of IVUS and QCA to Assess PCI and Atherosclerosis” at Erasmus University Rotterdam. Based on his Rotterdam experience, Prof. Dr. Yukio Ozaki proposed for the first time that intact fibrous cap ACS (IFC-ACS) by OCT and angioscopy would be plaque erosion (EHJ 2011), reported firstly integrated backscatter IVUS defined thin cap fibroatheroma (TCFA) in comparison with OCT (Circ J 2015), initially examine the fate of incomplete stent apposition (ISA) in DES by OCT (EHJ 2010). While Yukio Ozaki, Sadako Motoyama and Jagat Narula initially reported that positive remodeling (PR) and low attenuation plaque (LAP) are crucial factors in ACS lesions by CT angiography, they published these features could predict the occurrence of future ACS and play a role in the long-term prognosis for the first time (JACC 2007, JACC 2009 & JACC 2015). Subsequently, Dr. Ozaki’s CITATION INDEX has reached 7,214 by Pure System in Elsevier in December 2019.
Heart and vessels 34(12) 1899-1908 2019年12月 [査読有り]
It is known that incidence and short-term mortality rate of acute myocardial infarction (AMI) tend to be higher in the cold season. The aim of our study was to investigate the association of onset-season with patient characteristics and long-term ...
Cardiovascular intervention and therapeutics 34(4) 297-304 2019年10月 [査読有り]
This study evaluated whether radial access intervention had a lower risk of post-treatment adverse events in acute coronary syndrome (ACS) even in Japan where the use of a strong antithrombotic regimen was not approved. We retrospectively analyzed...
International journal of hematology 110(3) 285-294 2019年9月 [査読有り]
Soluble forms of platelet membrane proteins are released upon platelet activation. We previously reported that soluble C-type lectin-like receptor 2 (sCLEC-2) is released as a shed fragment (Shed CLEC-2) or as a whole molecule associated with plat...
Kawai H   Ohta M   Motoyama S   Hashimoto Y   Takahashi H   Muramatsu T   Sarai M   Narula J   Ozaki Y   
Prati F   Romagnoli E   Gatto L   La Manna A   Burzotta F   Ozaki Y   Marco V   Boi A   Fineschi M   Fabbiocchi F   Taglieri N   Niccoli G   Trani C   Versaci F   Calligaris G   Ruscica G   Di Giorgio A   Vergallo R   Albertucci M   Biondi-Zoccai G   Tamburino C   Crea F   Alfonso F   Arbustini E   CLIMA Investigators   
Background: A modestly elevated circulating D-dimer level may be relevant to coronary artery disease (CAD), but its prognostic value, both independently and in combination with estimated glomerular filtration rate (eGFR), for long-term death has n...
J. W. Eikelboom   S. J. Connolly   J. Bosch   G. R. Dagenais   R. G. Hart   O. Shestakovska   R. Diaz   M. Alings   E. M. Lonn   S. S. Anand   P. Widimsky   M. Hori   A. Avezum   L. S. Piegas   K. R. H. Branch   J. Probstfield   D. L. Bhatt   J. Zhu   Y. Liang   A. P. Maggioni   P. Lopez-Jaramillo   M. O'Donnell   A. K. Kakkar   K. A. A. Fox   A. N. Parkhomenko   G. Ertl   S. Stoerk   M. Keltai   L. Ryden   N. Pogosova   A. L. Dans   F. Lanas   P. J. Commerford   C. Torp-Pedersen   T. J. Guzik   P. B. Verhamme   D. Vinereanu   J. -H. Kim   A. M. Tonkin   B. S. Lewis   C. Felix   K. Yusoff   P. G. Steg   K. P. Metsarinne   N. Cook Bruns   F. Misselwitz   E. Chen   D. Leong   S. Yusuf   
NEW ENGLAND JOURNAL OF MEDICINE 377(14) 1319-1330 2017年10月
BACKGROUND
We evaluated whether rivaroxaban alone or in combination with aspirin would be more effective than aspirin alone for secondary cardiovascular prevention.
METHODS
In this double-blind trial, we randomly assigned 27,395 participants with ...
Background: According to troponin-based criteria of myocardial infarction (MI), patients without elevation of creatine kinase (CK), formerly classified as unstable angina (UA), are now diagnosed as non-ST-elevation MI (NSTEMI), but little is known...
Dexiao Huang   Takashi Muramatsu   Yingguang Li   Wenjie Yang   Yasuomi Nagahara   Miao Chu   Pieter Kitslaar   Masayoshi Sarai   Yukio Ozaki   Yiannis S. Chatzizisis   Fuhua Yan   Johan H. C. Reiber   Renhua Wu   Jun Pu   Shengxian Tu   
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING 33(7) 1101-1110 2017年7月
Characterization of endothelial shear stress (ESS) may allow for prediction of the progression of atherosclerosis. The aim of this investigation was to develop a non-invasive approach for in vivo assessment of ESS by coronary computed tomography a...
Ito H   Motoyama S   Sarai M   Kawai H   Nagahara Y   Harigaya H   Kan S   Naruse H   Ishii J   Ozaki Y   
Shiino K   Sugimoto K   Yamada A   Inuzuka H   Kato M   Sone M   Takada K   Sugimoto K   Takagi Y   Iwase M   Ozaki Y   
Naruse H   Ishii J   Okuyama R   Ohta M   Hashimoto T   Hattori K   Okumura M   Mori Y   Matsui S   Izawa H   Ozaki Y   
Ito H   Motoyama S   Sarai M   Kawai H   Nagahara Y   Takada K   Okumura M   Naruse H   Ishii J   Ozaki Y