European journal of neurology 31(3) e16158 2024年3月 [査読有り]
BACKGROUND AND PURPOSE: Multiple system atrophy (MSA) is a neurodegenerative disease with characteristic motor and autonomic symptoms. Impaired brain serotonergic innervation can be associated with various clinical indices of MSA; however, the rel...
Parkinsonism & related disorders 120 106012-106012 2024年1月 [査読有り]
INTRODUCTION: The King's Parkinson's Disease Pain Scale (KPPS)/King's Parkinson's Disease Pain Questionnaire (KPPQ) was developed as a tool to quantitatively assess pain in patients with Parkinson's disease (PwPD). Here, we conducted a Japanese mu...
Annals of clinical and translational neurology 2023年7月 [査読有り]
OBJECTIVE: Recent studies have revealed an association between Parkinson's disease (PD) and Fabry disease, a lysosomal storage disorder; however, the underlying mechanisms remain to be elucidated. This study aimed to investigate the enzymatic prop...
BACKGROUND: Parkinson's disease (PD) is associated with cognitive decline through multiple mechanisms, including Alzheimer's disease (AD) pathology and cortical Lewy body involvement. However, its underlying mechanisms remain unclear. Recently, AD...
Journal of movement disorders 16(1) 13-21 2023年1月 [査読有り]
This review summarizes improvements in understanding the pathophysiology and early clinical symptoms of multiple system atrophy (MSA) and advancements in diagnostic methods and disease-modifying therapies for the condition. In 2022, the Movement D...
2021 International Conference of Korean Movement Disorders Society, Best Oral Presentation Award,CSF Lipidomic Alterations Reflects Cognitive Decline and Neuronal Damage in Parkinson’s DiseaseYasuaki Mizutani, Sayuri Shima, Akihiro Ueda, Mizuki Ito, Hirohisa Watanabe