Miho Yumoto   Osamu Nishida   Kazuhiro Moriyama   Yasuyo Shimomura   Tomoyuki Nakamura   Naohide Kuriyama   Yoshitaka Hara   Shingo Yamada   
THERAPEUTIC APHERESIS AND DIALYSIS 15(4) 385-393 2011年8月
The high mobility group box 1 protein (HMGB1) is an alarmin that plays an important role in sepsis and has been recognized as a promising target with a wide therapeutic window; however, no drugs and devices are currently in practical use. We hypot...