The prognostic role of D-dimer in different types of heart failure (HF) is poorly understood. We investigated the prognostic value of D-dimer on admission, both independently and in combination with the Get With The Guidelines-Heart Failure (GWTG-...
Ian Baudi   Masanori Isogawa   Federica Moalli   Masaya Onishi   Keigo Kawashima   Yuji Ishida   Chise Tateno   Yusuke Sato   Hideyoshi Harashima   Hiroyasu Ito   Tetsuya Ishikawa   Takaji Wakita   Matteo Iannacone   Yasuhito Tanaka   
PLoS pathogens 17(5) e1009228 2021年5月
Virus infection, such as hepatitis B virus (HBV), occasionally causes endoplasmic reticulum (ER) stress. The unfolded protein response (UPR) is counteractive machinery to ER stress, and the failure of UPR to cope with ER stress results in cell dea...
Daisuke Ito   Hiroyasu Ito   Takayasu Ideta   Ayumu Kanbe   Soranobu Ninomiya   Masahito Shimizu   
Cell communication and signaling : CCS 19(1) 36-36 2021年3月
BACKGROUND: The skin wound healing process is regulated by various cytokines, chemokines, and growth factors. Recent reports have demonstrated that spermine/spermidine (SPD) promote wound healing through urokinase-type plasminogen activator (uPA)/...
Journal of gastroenterology and hepatology 36(3) 782-789 2021年3月
BACKGROUND AND AIM: The chronicity of hepatitis B virus (HBV) infection is the result of impaired HBV-specific immune responses that cannot eliminate or cure the infected hepatocytes efficiently. Previous studies have used immunodeficient mice suc...
Eri Nanizawa   Yuki Tamaki   Reika Sono   Rintaro Miyashita   Yumi Hayashi   Ayumu Kanbe   Hiroyasu Ito   Tetsuya Ishikawa   
Biochemistry and biophysics reports 22 100736-100736 2020年7月
Obesity and high-fat diet (HFD) are known to cause proinflammatory and procoagulation states and suggested to become a risk of developing thromboembolic diseases. Non-alcoholic fatty liver disease (NAFLD) is usually associated with obesity and HFD...