研究者氏名	竹内俊幸

URL
所属	藤田医科大学
部署	医学部医学科分子腫瘍学
職名	助教
学位	博士(生命科学)(鳥取大学)
J-Global ID	201801008046891200

研究キーワード

腫瘍 ,転写因子 ,遺伝子発現

研究分野

ライフサイエンス / 分子生物学 /

経歴

2017年10月

現在

藤田医科大学医学部分子腫瘍学助教

2006年3月

2017年9月

株式会社Oncomics 研究部課長

2001年7月

2006年2月

社団法人バイオ産業情報化コンソシーアム特別研究員

2001年4月

2001年6月

鳥取大学医学部研究生

学歴

1998年4月

2001年3月

鳥取大学大学院医学系研究科博士後期課程

1996年4月

1998年3月

鳥取大学大学院医学系研究科博士前期課程

1992年4月

1996年3月

鳥取大学医学部生命科学科

論文

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Shuta Tomida Toshiyuki Takeuchi Yukako Shimada Chinatsu Arima Keitaro Matsuo Tetsuya Mitsudomi Yasushi Yatabe Takashi Takahashi

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(17) 2793-9 2009年6月 [査読有り]

PURPOSE: In order to aid the development of patient-tailored therapeutics, we attempted to identify a relapse-related signature that allows selection of a group of adenocarcinoma patients with a high probability of relapse. PATIENTS AND METHODS: W...

Relationship of deregulated signaling converging onto mTOR with prognosis and classification of lung adenocarcinoma shown by two independent in silico analyses.

Hiromichi Ebi Shuta Tomida Toshiyuki Takeuchi Chinatsu Arima Takahiko Sato Tetsuya Mitsudomi Yasushi Yatabe Hirotaka Osada Takashi Takahashi

Cancer research 69(9) 4027-35 2009年5月 [査読有り]

There is marked disparity with a slight overlap among prognosis-predictive signatures reported thus far for lung cancers. In this study, we aimed at linking poor prognosis with particular pathways and/or functions of the gene sets involved to bett...

Roles of achaete-scute homologue 1 in DKK1 and E-cadherin repression and neuroendocrine differentiation in lung cancer.

Hirotaka Osada Shuta Tomida Yasushi Yatabe Yoshio Tatematsu Toshiyuki Takeuchi Hideki Murakami Yutaka Kondo Yoshitaka Sekido Takashi Takahashi

Cancer research 68(6) 1647-55 2008年3月 [査読有り]

The proneural basic-helix-loop-helix protein achaete-scute homologue 1 (ASH1) is expressed in a very limited spectrum of normal and cancerous cells in a lineage-specific manner, including normal pulmonary neuroendocrine cells and lung cancer cells...

Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92

Hideo Matsubara, Toshiyuki Takeuchi, Eri Nishikawa, Kiyoshi Yanagisawa, Yoji Hayashita, Hiromichi Ebi, Hideki Yamada, Motoshi Suzuki, Masato Nagino, Yuji Nimura, Hirotaka Osada, Takashi Takahashi

Oncogene 26(41) 6099-6105 2007年9月 [査読有り]

Amplification and overexpression of the miR- 17- 92 microRNAs ( miRNA) cluster at 13q31.3 has recently reported, with pointers to functional involvement in the development of B- cell lymphomas and lung cancers. In the present study, we show that i...

Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors.

Toshiyuki Takeuchi Shuta Tomida Yasushi Yatabe Takayuki Kosaka Hirotaka Osada Kiyoshi Yanagisawa Tetsuya Mitsudomi Takashi Takahashi

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 24(11) 1679-88 2006年4月 [査読有り]

PURPOSE: This study was conducted to gain insight into the relationship between expression profiles and underlying genetic changes, which are known to be important for the pathogenesis of lung cancers. METHODS: Expression profiles of 18,175 unique...