Disturbances of the circadian rhythm are involved in the pathophysiology of bipolar disorder (BD), schizophrenia (SCZ) and major depressive disorder (MDD). Specifically, because clock gene dysfunction is good candidate for enhancing the susceptibi...
Taro Kishi   Yasuhisa Fukuo   Tomo Okochi   Kunihiro Kawashima   Masatsugu Moriwaki   Osamu Furukawa   Kiyoshi Fujita   Giovanna M. Musso   Christoph U. Correll   John M. Kane   Nakao Iwata   
NEUROMOLECULAR MEDICINE 14(2) 131-138 2012年6月 [査読有り]
Recently, schizophrenia endophenotypes have been actively investigated to better understand the pathophysiology of schizophrenia. Past studies have shown that cognitive functions, including working memory and executive function, correlate with aco...
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 159B(4) 456-464 2012年6月 [査読有り]
Recent GWAS demonstrated an association between candidate genes located at region 6p22.1 and schizophrenia. This region has been reported to house certain candidate SNPs, which may be associated with schizophrenia at HIST1H2BJ, PRSS16, and PGBD1. ...
Our genome-wide association study of schizophrenia found association signals at the Kalirin gene (KALRN) and EPH receptor B1 gene (EPHB1) in a Japanese population. The importance of these synaptogenic pathway genes in schizophrenia is gaining inde...
Kishi T   Fukuo Y   Okochi T   Kawashima K   Kitajima T   Inada T   Ozaki N   Musso GM   Kane JM   Correll CU   Iwata N   
Human psychopharmacology 27(1) 63-69 2012年1月 [査読有り]