研究者氏名	瀬戸孝一

URL
所属	藤田医科大学
部署	研究推進本部　未来共創イノベーションセンター
職名
学位	薬学博士
J-Global ID	201901010015875519

研究分野

情報通信 / 生命、健康、医療情報学 /
ライフサイエンス / 分子生物学 /
ライフサイエンス / 薬系化学、創薬科学 /
ライフサイエンス / 薬系衛生、生物化学 /

経歴

2020年2月

現在

株式会社D&P Labo. 代表取締役社長

2019年4月

現在

藤田医科大学研究支援推進本部産学連携推進センター教授、産学連携コーディネーター

2019年4月

2021年2月

京都大学客員研究員

2014年4月

2020年3月

立教大学理学部兼任講師

1991年4月

2019年3月

ゼリア新薬工業株式会社中央研究所

論文

<2 3 456 >

Polaprezinc, a gastroprotective agent: attenuation of monochloramine-evoked gastric DNA fragmentation

H Suzuki M Mori K Seto S Nagahashi C Kawaguchi H Morita M Suzuki S Miura T Yoneta H Ishii

JOURNAL OF GASTROENTEROLOGY 34 43-46 1999年12月 [査読有り]

We previously reported that NH2Cl induced extensive DNA fragmentation in gastric cells. Polaprezinc, a zinc-carnosine chelate compound, is reported to be a potent antioxidant in gastric mucosa. The present study was designed to examine whether pol...

Ethanol intake preceding Helicobacter pylori inoculation promotes gastric mucosal inflammation in Mongolian gerbils

H Suzuki M Mori K Seto S Nagahashi C Kawaguchi A Kai Y Akiba M Suzuki M Suematsu S Miura H Ishii

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 14(11) 1062-1069 1999年11月 [査読有り]

Background: Mongolian gerbils have been reported to be a suitable model for Helicobacter pylori-associated gastric mucosal injury, including gastric cancer. Although ethanol is known to be one of the harmful substances in the gastric mucosa, the r...

Effect of polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc), a novel antiulcer agent containing zinc, on cellular proliferation: Role of insulin-like growth factor I

K Seto T Yoneta H Suda H Tamaki

BIOCHEMICAL PHARMACOLOGY 58(2) 245-250 1999年7月 [査読有り]

The effect of polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc), a novel antiulcer drug containing zinc, on cellular proliferation was studied using cultured cells. In human umbilical vein endothelial cells (HUVEC) or human foreskin fibroblast...

Helicobacter pylori-associated gastric pro- and antioxidant formation in Mongolian gerbils

H Suzuki M Mori K Seto AM Kai C Kawaguchi M Suzuki M Suematsu T Yoneta S Miura H Ishii

FREE RADICAL BIOLOGY AND MEDICINE 26(5-6) 679-684 1999年3月 [査読有り]

Helicobacter pylori colonized gastric mucosa is manifest in a significant neutrophil infiltration with an extensive level of oxyradical formation. Mongolian gerbil is one of the excellent models for H. pylori-infection. The present study was desig...

Paracrine upregulation of VEGF receptor mRNA in endothelial cells by hypoxia-exposed Hep G2 cells

H Suzuki K Seto Y Shinoda M Mori Y Ishimura M Suematsu H Ishii

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 276(1) G92-G97 1999年1月 [査読有り]

Although vascular endothelial growth factor (VEGF) plays a role in the growth of hypervascular tumors, mechanisms for paracrine regulation of its receptor expression on vascular endothelial cells remain unknown. This study aimed to investigate whe...