研究者氏名	全並賢二
	ゼンナミケンジ
URL
所属	藤田医科大学
部署	医学部医学科
職名	講師
学位	博士（医学）
J-Global ID	201901013493631527

研究分野

ライフサイエンス / 泌尿器科学 /

論文

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Targeting lactate dehydrogenase‑A promotes docetaxel‑induced cytotoxicity predominantly in castration‑resistant prostate cancer cells.

Hiroyuki Muramatsu Makoto Sumitomo Shingo Morinaga Keishi Kajikawa Ikuo Kobayashi Genya Nishikawa Yoshiharu Kato Masahito Watanabe Kenji Zennami Kent Kanao Kogenta Nakamura Susumu Suzuki Kazuhiro Yoshikawa

Oncology reports 42(1) 224-230 2019年7月

Docetaxel (DOC) is one of the most effective chemotherapeutic agents against castration‑resistant prostate cancer (CRPC). Despite an impressive initial clinical response, the majority of patients eventually develop resistance to DOC. In tumor meta...

PDCD4 Is an Androgen-Repressed Tumor Suppressor that Regulates Prostate Cancer Growth and Castration Resistance.

Kenji Zennami Su Mi Choi Ross Liao Ying Li Wikum Dinalankara Luigi Marchionni Fatema H Rafiqi Akira Kurozumi Koji Hatano Shawn E Lupold

Molecular cancer research : MCR 17(2) 618-627 2019年2月

Androgen receptor (AR) transcriptional activity contributes to prostate cancer development and castration resistance. The growth and survival pathways driven by AR remain incompletely defined. Here, we found PDCD4 to be a new target of AR signalin...

Impact of a novel biopsy instrument with a 25-mm side-notch needle on the detection of prostate cancer in transrectal biopsy.

Kent Kanao Keishi Kajikawa Ikuo Kobayashi Shingo Morinaga Hiroyuki Muramatsu Genya Nishikawa Masahito Watanabe Kenji Zennami Kogenta Nakamura Makoto Sumitomo

International journal of urology : official journal of the Japanese Urological Association 25(8) 746-751 2018年8月

OBJECTIVES: To evaluate the impact of a novel biopsy instrument that extends the length of the side-notch on the detection of prostate cancer in transrectal needle biopsy. METHODS: We collaborated with a biopsy needle manufacturer and developed a ...

Clinical pharmacokinetics and pharmacodynamic target attainment of pazufloxacin in prostate tissue: Dosing considerations for prostatitis.

Kogenta Nakamura Kazuro Ikawa Genya Nishikawa Ikuo Kobayashi Masahiro Narushima Hiroyuki Muramatsu Shingo Morinaga Keishi Kajikawa Yoshiharu Kato Masahito Watanabe Kenji Zennami Kent Kanao Norifumi Morikawa Makoto Sumitomo

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 23(12) 809-813 2017年12月

The present study examined the clinical pharmacokinetics of pazufloxacin in prostate tissue and estimated the probability of target attainment for tissue-specific pharmacodynamic goals related to treating prostatitis using various intravenous dosi...

Optimal method for measuring tumor extent in needle biopsy specimens to identify small-volume prostate cancer.

Keishi Kajikawa Kent Kanao Ikuo Kobayashi Genya Nishikawa Takahiko Yoshizawa Yoshiharu Kato Masahito Watanabe Kenji Zennami Kogenta Nakamura Makoto Sumitomo

International journal of urology : official journal of the Japanese Urological Association 23(1) 62-8 2016年1月

OBJECTIVES: To compare various methods for measuring tumor extent in prostate biopsy specimens to identify small-volume prostate cancer. METHODS: A total of 100 radical prostatectomy specimens were retrospectively analyzed. Receiver operating char...