Digestive diseases and sciences 60(6) 1699-706 2015年6月
BACKGROUND AND AIM: The liver has a high capacity of its regeneration. Most hepatic cells are quiescent unless otherwise stimulated such as their injury or ablation. A previous study suggest that pre-activated hepatic cells have a positive effect ...
Skin wound healing is a complex process involving several stages that include inflammation, proliferation, and remodeling. In the inflammatory phase, pro-inflammatory cytokines and chemokines are induced at the wound site and, they contribute to t...
Hiroyasu Ito Tatsuya Ando Yuko Arioka Kuniaki Saito Mitsuru Seishima
Immunology 144(4) 621-30 2015年4月
Toll-like receptor (TLR) agonists have been shown to have anti-tumour activity in basic research and clinical studies. However, TLR agonist monotherapy does not sufficiently eliminate tumours. Activation of the innate immune response by TLR agonis...
Hiroyasu Ito Tatsuya Ando Hideyuki Ogiso Yuko Arioka Mitsuru Seishima
Cancer immunology, immunotherapy : CII 64(4) 429-36 2015年4月
Toll-like receptor (TLR) agonists have been shown to have anti-tumor activity in basic research and clinical studies. However, TLR agonist monotherapy in cancer treatment dose not sufficiently eliminate tumors. Activation of the innate immune resp...
Tatsuya Ando Hiroyasu Ito Yuko Arioka Hideyuki Ogiso Mitsuru Seishima
Oncology reports 33(2) 826-32 2015年2月
α-galactosylceramide (GalCer), which is a natural killer T (NKT) cell ligand, has been reported to exert therapeutic effects against cancer in humans and mice. Toll-like receptor (TLR) agonists systemically or locally boost antitumor efficacy in m...
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医学部