Human stem cell-derived organoid culture enables the in vitro analysis of the cellular function in three-dimensional aggregates mimicking native organs, and also provides a valuable source of specific cell types in the human body. We previously es...
The hypothalamus is comprised of heterogenous cell populations and includes highly complex neural circuits that regulate the autonomic nerve system. Its dysfunction therefore results in severe endocrine disorders. Although recent experiments have ...
Hiroshi Nagasaki   Akira Nakashima   Yoko S. Kaneko   Yu Kodani   Takeshi Takayanagi   Mitsuyasu Itoh   Kazunao Kondo   Toshiharu Nagatsu   Yoji Hamada   Miyuki Ota   Akira Ota   
JOURNAL OF NEURAL TRANSMISSION 121(1) 91-103 2014年1月
In aripiprazole-treated PC12 cells, we previously showed that the mitochondrial membrane potential (Delta psi(m)) was rather increased in spite of lowered cytochrome c oxidase activity. To address these inconsistent results, we focused the NADPH g...