JAPANESE JOURNAL OF NEUROPSYCHOPHARMACOLOGY 34(3) 67-79 2014年6月 [査読有り]
Schizophrenia and bipolar disorder are severe neuropsychiatric disorders, affecting about 1% of the population. Identifying endophenotypes in the brains of neuropsychiatric patients is now considered the way to understand the underlying mechanisms...
Katherine G. Akers Alonso Martinez-Canabal Leonardo Restivo Adelaide P. Yiu Antonietta De Cristofaro Hwa-Lin (Liz) Hsiang Anne L. Wheeler Axel Guskjolen Yosuke Niibori Hirotaka Shoji Koji Ohira Blake A. Richards Tsuyoshi Miyakawa Sheena A. Josselyn Paul W. Frankland
SCIENCE 344(6184) 598-602 2014年5月 [査読有り]
Throughout life, new neurons are continuously added to the dentate gyrus. As this continuous addition remodels hippocampal circuits, computational models predict that neurogenesis leads to degradation or forgetting of established memories. Consist...
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (85) 2014年3月 [査読有り]
The contextual and cued fear conditioning test is one of the behavioral tests that assesses the ability of mice to learn and remember an association between environmental cues and aversive experiences. In this test, mice are placed into a conditio...
JOURNAL OF NEUROSCIENCE 33(36) 14549-+ 2013年9月 [査読有り]
The noradrenergic (NA) projections arising from the locus ceruleus (LC) to the amygdala and bed nucleus of the stria terminalis have been implicated in the formation of emotional memory. Since NA neurons in the LC (LC-NA neurons) abundantly expres...
JOURNAL OF ETHNOPHARMACOLOGY 149(1) 93-102 2013年8月 [査読有り]
Ethnopharmacological relevance: A traditional Japanese (Kampo) medicine, yokukansan, has long been used to treat neurosis, insomnia, and night crying and irritability in children. Recently, this medicine has reported to improve the behavioral and ...
Maturation and integration of neurons and grial cells in the hippocampus is considered to be essential for regulating endocrine, affective, and congnitive functions, and the disruption of such process may cause mental illness. Previously, we have ...
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