Acute lung injury (ALI) occurs in patients with severe sepsis and has a mortality rate of 40%-60%. Severe sepsis promotes the release of histones from dying cells, which can induce platelet aggregation, activate coagulation and cause endothelial c...
Monocarboxylates, such as lactate and pyruvate, are precursors for biosynthetic pathways, including those for glucose, lipids, and amino acids via the tricarboxylic acid (TCA) cycle and adjacent metabolic networks. The transportation of monocarbox...
Yukako Ohyama Matthew B Renfrow Jan Novak Kazuo Takahashi
Journal of clinical medicine 10(16) 2021年8月
IgA nephropathy (IgAN), the most common primary glomerular disease worldwide, is characterized by glomerular deposition of IgA1-containing immune complexes. The IgA1 hinge region (HR) has up to six clustered O-glycans consisting of Ser/Thr-linked ...
国際IgAシンポジウムにて研究成果を評価され受賞、その内容を大学院生の研究指導にフィードバックした。[Jean Berger Prize]Kazuo Takahashi, Hitoshi Suzuki, Koshi Yamada, Stacy Hall, Zina Moldoveanu, Knud Poulsen, Mogens Kilian, Jiri Mestecky, Bruce A. Julian, Matthew B. Renfrow, Jan Novak. Molecular Characterization of IgA1 Secreted by IgA1-producing Cell Lines from Patients with IgA Nephropathy. 13th International Symposium on IgA Nephropathy; 4-6th June, 2013, Nanjing, China
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医学部