International Journal of Molecular Sciences 23(5) 2555-2555 2022年2月 [査読有り]
Calcium homeostasis endoplasmic reticulum protein (CHERP) is colocalized with the inositol 1,4,5-trisphosphate receptor (IP3R) in the endoplasmic reticulum or perinuclear region, and has been involved in intracellular calcium signaling. Structural...
Yuta Otani Ken-ichi Fujita Toshiki Kameyama Akila Mayeda
International Journal of Molecular Sciences 22(12) 6519-6519 2021年6月 [査読有り]
Using TSG101 pre-mRNA, we previously discovered cancer-specific re-splicing of mature mRNA that generates aberrant transcripts/proteins. The fact that mRNA is aberrantly re-spliced in various cancer cells implies there must be an important mechani...
International journal of molecular sciences 21(6) 2020年3月 [査読有り]
Human transcriptomes are more divergent than genes and contribute to the sophistication of life. This divergence is derived from various isoforms arising from alternative splicing. In addition, alternative splicing regulated by spliceosomal factor...
The TREX complex integrates information from nuclear mRNA processing events to ensure the timely export of mRNA to the cytoplasm. In humans, UAP56 and its paralog URH49 form distinct complexes, the TREX complex and the AREX complex, respectively, ...
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