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研究者リスト >> 渡邉毅一

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渡邉毅一

研究者氏名	渡邉毅一
	ワタナベキイチ
URL
所属	藤田医科大学
部署	国際再生医療センター
職名	准教授
科研費研究者番号	90392183
J-Global ID	202101015665572510

研究分野

ライフサイエンス / 分子生物学 /
ライフサイエンス / 発生生物学 /
ライフサイエンス / 神経科学一般 /

論文

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Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix.

Morio Ueno Michiru Matsumura Kiichi Watanabe Takahiro Nakamura Fumitaka Osakada Masayo Takahashi Hiroshi Kawasaki Shigeru Kinoshita Yoshiki Sasai

Proceedings of the National Academy of Sciences of the United States of America 103(25) 9554-9 2006年6月

Here we report a human-derived material with potent inductive activity that selectively converts ES cells into neural tissues. Both mouse and human ES cells efficiently differentiate into neural precursors when cultured on the matrix components of...

Fluorescence-activated cell sorting-based purification of embryonic stem cell-derived neural precursors averts tumor formation after transplantation.

Hitoshi Fukuda Jun Takahashi Kiichi Watanabe Hideki Hayashi Asuka Morizane Masaomi Koyanagi Yoshiki Sasai Nobuo Hashimoto

Stem cells (Dayton, Ohio) 24(3) 763-71 2006年3月

The differentiation of dopaminergic (DA) neurons from mouse embryonic stem cells (ESCs) can be efficiently induced, making these neurons a potential source for transplantation as a treatment for Parkinson's disease, a condition characterized by th...

Generation of cerebellar neuron precursors from embryonic stem cells.

Hong-Lin Su Keiko Muguruma Mami Matsuo-Takasaki Mineko Kengaku Kiichi Watanabe Yoshiki Sasai

Developmental biology 290(2) 287-96 2006年2月

Here, we report in vitro generation of Math1+ cerebellar granule cell precursors and Purkinje cells from ES cells by using soluble patterning signals. When neural progenitors induced from ES cells in a serum-free suspension culture are subsequentl...

Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells.

Hanako Ikeda Fumitaka Osakada Kiichi Watanabe Kenji Mizuseki Tomoko Haraguchi Hiroyuki Miyoshi Daisuke Kamiya Yoshihito Honda Noriaki Sasai Nagahisa Yoshimura Masayo Takahashi Yoshiki Sasai

Proceedings of the National Academy of Sciences of the United States of America 102(32) 11331-6 2005年8月

We report directed differentiaion of retinal precursors in vitro from mouse ES cells. Six3+ rostral brain progenitors are generated by culturing ES cells under serum-free suspension conditions (SFEB culture) in the presence of Wnt and Nodal antago...

[In vitro differentiation of telencephalic precursors from ES cells].

Kiichi Watanabe Yoshiki Sasai

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 50(6 Suppl) 711-6 2005年5月