OBJECTIVE: MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and play essential roles in the pathogenesis of cardiovascular disease. Previous cross-sectional studies showed that the levels of several circulating miRNA are a...
Nutrition (Burbank, Los Angeles County, Calif.) 81 110951-110951 2021年1月
OBJECTIVES: A diet rich in fish and ω-3 polyunsaturated fatty acids (PUFAs) has been thought to reduce the risk for cardiovascular disease (CVD). The beneficial effects of fish oil and ω-3 PUFA on CVD can be mediated by epigenetic status of the ge...
BACKGROUND: MicroRNAs (miRNAs) play crucial roles in the development of various diseases, including chronic kidney disease (CKD). Although previous studies in clinically severe patients have investigated associations between CKD and miRNAs, with p...
Thioredoxin-interacting protein (TXNIP) inhibits the activity of thioredoxin (TXN), leading to increased oxidative stress. Expression of the TXNIP gene is regulated by DNA methylation. However, no study has reported the influence of lifestyle fact...
IshiharaY   Yamada H   Munetuna E   Yamazaki M   Hatta T   Iwahara A   Ohashi K   Ishikawa H   Maeda K   Ando Y   Tsuboi Y   Fujii R   Suzuki K