Human Molecular Genetics 32(8) 1301-1312 2022年11月 [査読有り]
Fukuyama congenital muscular dystrophy (FCMD) is an autosomal recessive disorder caused by fukutin (FKTN) gene mutations. FCMD is the second most common form of childhood muscular dystrophy in Japan, and the most patients possess a homozygous retr...
The striatum, a main component of the basal ganglia, is a critical part of the motor and reward systems of the brain. It consists of GABAergic and cholinergic neurons and receives projections of dopaminergic, glutamatergic, and serotonergic neuron...
Chromosome 8 open reading frame 46 (C8orf46), a human protein-coding gene, has recently been named Vexin. A recent study indicated that Vexin is involved in embryonic neurogenesis. Additionally, some transcriptomic studies detected changes in the ...
Koshimizu H   Nogawa S   Asano S   Ikeda M   Iwata N   Takahashi S   Saito K   Miyakawa T   
Translational Psychiatry 9(1) 52 2019年1月 [査読有り]
Major depressive disorder (MDD) is a common and disabling psychiatric disorder. A recent mega analysis of genome-wide association studies (GWASs) identified 44 loci associated with MDD, though most of the genetic etiologies of the MDD/psychologica...
Koshimizu H   Ohira K   Hagihara H   Takao K   Takagi T   Kataoka M   Ishii S   Takahashi M   Miyakawa T   
Society for Neuroscience 43rd Annual Meeting, San Diego, CA 2013年11月
① CRH結合蛋白質の可視化(CRH-BP-pHluorin による生細胞中での輸送・放出過程の可視化。昭和大学、香川大学、横浜薬科大との共同研究。詳細はAdachi et al., J. Neurochem. 2018)
*本研究シーズに関する産学共同研究の問い合わせは藤田医科大学産学連携推進センター(fuji-san@fujita-hu.ac.jp)まで