Tsukamoto, K.   Miura, F.   Fujito, N.T.   Yoshizaki, G.   Nonaka, M.   
Molecular Biology and Evolution 29(10) 3071-3079 2012年10月 [査読有り]
On an evolutionary time scale, polymorphic alleles are believed to have a short life, persisting at most tens of millions of years even under long-term balancing selection. Here, we report highly diverged trans-species dimorphism of the proteasome...
Katsumura, T.   Oda, S.   Tsukamoto, K.   Sekiya, Y.   Yamashita, T.   Aso, M.   Hata, M.   Nonaka, M.   Mano, S.   Ishida, H.   Mitani, H.   Kawamura, S.   Oota, H.   
Anthropological Science 120(1) 81-89 2012年4月
It has been generally thought that a tiny freshwater fish, medaka (Oryzias latipes), has expanded its habitat into the Japanese archipelago as wet-rice cultivation spread across the region, and hence the distribution of medaka should be a matter o...
Miura, F.   Tsukamoto, K.   Mehta, R.B.   Naruse, K.   Magtoon, W.   Nonaka, M.   
Proceedings of the National Academy of Sciences of the United States of America 107(50) 21599-21604 2010年12月 [査読有り]
The proteasome subunit beta-type 8 (PSMB8) gene in the jawed vertebrate MHC genomic region encodes a catalytic subunit of the immunoproteasome involved in the generation of peptides to be presented by the MHC class I molecules. A teleost, the meda...
Tsukamoto, K.   Sakaizumi, M.   Hata, M.   Sawara, Y.   Eah, J.   Kim, C.-B.   Nonaka, M.   
Molecular Biology and Evolution 26(4) 769-781 2009年4月 [査読有り]
Sequence comparison of the medaka, Oryzias latipes, major histocompatibility complex (MHC) class I region between two inbred strains, the HNI (derived from the Northern Population) and the Hd-rR (from the Southern Population), revealed a similar t...
Tsukamoto, K.   Hayashi, S.   Matsuo, M.Y.   Nonaka, M.I.   Kondo, M.   Shima, A.   Asakawa, S.   Shimizu, N.   Nonaka, M.   
Immunogenetics 57(6) 420-431 2005年7月 [査読有り]
The major histocompatibility complex (MHC) is present at a single chromosomal locus of all jawed vertebrate analyzed so far, from sharks to mammals, except for teleosts whose orthologs of the mammalian MHC-encoded genes are dispersed at several ch...