Masanori Nakanishi   Tomohiro Mizuno   Fumihiro Mizokami   Takenao Koseki   Kazuo Takahashi   Naotake Tsuboi   Michael Katz   Jeannie K Lee   Shigeki Yamada   
Journal of clinical pharmacy and therapeutics 46(1) 114-120 2020年9月 [査読有り]
WHAT IS KNOWN AND OBJECTIVE: Hypertension (HTN) and chronic kidney disease (CKD) are recognized as silent killers because they are asymptomatic conditions that contribute to the burden of multiple comorbidities. The achievement of a blood pressure...
Renal anemia in chronic kidney disease is treated with recombinant human erythropoietin (rhEPO). However, some patients with anemia do not respond well to rhEPO, emphasizing the need for a more biocompatible EPO. Differentiation protocols for hepa...
A common renal disease, immunoglobulin A (IgA) nephropathy (IgAN), is associated with glomerular deposition of IgA1-containing immune complexes. IgA1 hinge region (HR) has up to six clustered O-glycans consisting of Ser/Thr-linked N-acetylgalactos...
Fumihiro Mizokami   Tomohiro Mizuno   Koichiro Kanamori   Sakiko Oyama   Tadashi Nagamatsu   Jeannie K Lee   Tomoharu Kobayashi   
Geriatrics & gerontology international 19(12) 1275-1281 2019年12月 [査読有り]
AIM: To analyze the impact of clinical medication reviews (CMR) on reducing unplanned hospitalizations owing to polypharmacy among older adults using an intervention. METHODS: Our meta-analysis complied with PRISMA guidelines. The literature revie...
European journal of pharmacology 826 48-55 2018年5月 [査読有り]
Extracellular histones induce lethal thrombosis by promoting platelet aggregation, neutrophil migration, and cell injuries. Heparin, which has negative charges, can bind to extracellular histones; however, heparin strongly inhibits the activation ...