T. Inagi   M. Suzuki   M. Osumi   H. Bito   
JOURNAL OF HOSPITAL INFECTION 89(1) 61-68 2015年1月
Background: Surgical site infection (SSI) after colorectal surgery is the leading cause of postoperative morbidity. Opioids induce immunosuppression through activation of mu-opioid receptors expressed on leucocytes, and through opioid withdrawal. ...