研究者氏名	山崎未来

URL
所属	藤田医科大学
部署	医学部医学科衛生学
職名	講師
学位	博士(医療科学)
J-Global ID	201901005807798674

研究分野

ライフサイエンス / 栄養学、健康科学 /
ライフサイエンス / 代謝、内分泌学 /
ライフサイエンス / 分子生物学 /

経歴

2023年10月

現在

藤田医科大学医学部医学科衛生学講師

2023年4月

2023年9月

香川県立保健医療大学保健医療学部臨床検査学科講師

2019年4月

2023年3月

香川県立保健医療大学保健医療学部臨床検査学科助教

2017年4月

2019年3月

藤田医科大学大学院保健学研究科日本学術振興会特別研究員DC2

論文

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Interaction between Prenatal and Postnatal Exposure to High-Fructose Corn Syrup Increases Gene Expression of Tnfa in Hippocampus of Offspring.

Mirai Yamazaki Hiroya Yamada Eiji Munetsuna Yoshitaka Ando Itsuki Kageyama Nao Sadamoto Yuki Nouchi Atsushi Teshigawara Genki Mizuno Hiroaki Ishikawa Koji Suzuki Shuji Hashimoto Koji Ohashi

Journal of nutritional science and vitaminology 69(4) 237-242 2023年 [査読有り]

Concerns about the negative intergenerational effects of excessive fructose intake are being raised, with evidence suggesting that prenatal fructose intake increases susceptibility to metabolic and cognitive dysfunction later in life. In the prese...

Effects of High-Fructose Corn Syrup Intake on Glucocorticoid Metabolism in Rats During Childhood, Adolescence and Adulthood.

Yuki Nouchi Eiji Munetsuna Hiroya Yamada Mirai Yamazaki Yoshitaka Ando Genki Mizuno Ryosuke Fujii Itsuki Kageyama Takuya Wakasugi Tomohide Sakakibara Atsushi Teshigawara Hiroaki Ishikawa Yohei Shimono Koji Suzuki Shuji Hashimoto Koji Ohashi

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 130(12) 814-820 2022年12月 [査読有り]

The consumption of high-fructose corn syrup (HFCS) has been increasing in recent decades, especially among children. Some reports suggest that children and adolescents are more sensitive to the adverse effects of fructose intake than adults. Howev...

Intake of vegetables and fruits rich in provitamin A is positively associated with aryl hydrocarbon receptor repressor DNA methylation in a Japanese population.

Yoshiki Tsuboi Hiroya Yamada Eiji Munetsuna Ryosuke Fujii Mirai Yamazaki Yoshitaka Ando Genki Mizuno Yuji Hattori Hiroaki Ishikawa Koji Ohashi Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

Nutrition research (New York, N.Y.) 107 206-217 2022年11月 [査読有り]

DNA methylation can be affected by numerous lifestyle factors, including diet. Tobacco smoking induces aryl hydrocarbon receptor repressor (AHRR) DNA hypomethylation, which increases the risk of lung and other cancers. However, no lifestyle habits...

High-fructose corn syrup intake has stronger effects on the transcription level of hepatic lipid metabolism-related genes, via DNA methylation modification, in childhood and adolescence than in other generations.

Genki Mizuno Hiroya Yamada Eiji Munetsuna Yoshitaka Ando Atsushi Teshigawara Manaka Ito Itsuki Kageyama Yuki Nouchi Takuya Wakasugi Tomohide Sakakibara Mirai Yamazaki Ryosuke Fujii Hiroaki Ishikawa Koji Suzuki Shuji Hashimoto Koji Ohashi

Life sciences 301 120638-120638 2022年7月 [査読有り]

AIMS: This study aimed to analyze differences in sensitivity to hepatic lipid metabolism at different ages, through DNA methylation, using an experimental rat model of high-fructose corn syrup (HFCS) intake. MAIN METHODS: The experimental was divi...

Circulating microRNA-27a and -133a are negatively associated with incident hypertension: a five-year longitudinal population-based study.

Koji Suzuki Hiroya Yamada Ryosuke Fujii Eiji Munetsuna Mirai Yamazaki Yoshitaka Ando Koji Ohashi Hiroaki Ishikawa Genki Mizuno Yohiski Tsuboi Shuji Hashimoto Nobuyuki Hamajima

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 27(5) 496-502 2022年7月 [査読有り]

BACKGROUND: Previous cross-sectional studies have shown that several circulating microRNA levels are associated with hypertension, but there are no prospective studies among general populations. OBJECTIVE: We evaluated the impact of circulating in...