研究者氏名	山崎未来

URL
所属	藤田医科大学
部署	医学部医学科衛生学
職名	講師
学位	博士(医療科学)
J-Global ID	201901005807798674

研究分野

ライフサイエンス / 栄養学、健康科学 /
ライフサイエンス / 代謝、内分泌学 /
ライフサイエンス / 分子生物学 /

経歴

2023年10月

現在

藤田医科大学医学部医学科衛生学講師

2023年4月

2023年9月

香川県立保健医療大学保健医療学部臨床検査学科講師

2019年4月

2023年3月

香川県立保健医療大学保健医療学部臨床検査学科助教

2017年4月

2019年3月

藤田医科大学大学院保健学研究科日本学術振興会特別研究員DC2

論文

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Increased risk of cancer mortality by smoking-induced aryl hydrocarbon receptor repressor DNA hypomethylation in Japanese population: A long-term cohort study.

Yoshiki Tsuboi Hiroya Yamada Eiji Munetsuna Ryosuke Fujii Mirai Yamazaki Yoshitaka Ando Genki Mizuno Yuji Hattori Hiroaki Ishikawa Koji Ohashi Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

Cancer epidemiology 78 102162-102162 2022年6月 [査読有り]

BACKGROUND: Smoking is well known to be a major risk factor for cancer, and to decrease the levels of aryl hydrocarbon receptor repressor (AHRR) DNA methylation. AHRR is a key regulator for AHR signaling, which is involved in chemical metabolism a...

Association of drinking behaviors with TXNIP DNA methylation levels in leukocytes among the general Japanese population.

Keisuke Maeda Hiroya Yamada Eiji Munetsuna Ryosuke Fujii Mirai Yamazaki Yoshitaka Ando Genki Mizuno Hiroaki Ishikawa Koji Ohashi Yoshiki Tsuboi Yuji Hattori Yuya Ishihara Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

The American journal of drug and alcohol abuse 48(3) 302-310 2022年5月 [査読有り]

Background: Thioredoxin-interacting protein (TXNIP) controls the cellular redox balance by binding to and inhibiting the expression and function of thioredoxin. DNA methylation of the TXNIP gene is involved in the regulation of TXNIP mRNA expressi...

Maternal high-fructose corn syrup consumption causes insulin resistance and hyperlipidemia in offspring via DNA methylation of the Pparα promoter region.

Yoshitaka Ando Hiroya Yamada Eiji Munetsuna Mirai Yamazaki Itsuki Kageyama Atsushi Teshigawara Yuki Nouchi Ryosuke Fujii Genki Mizuno Nao Sadamoto Hiroaki Ishikawa Koji Suzuki Shuji Hashimoto Koji Ohashi

The Journal of nutritional biochemistry 103 108951-108951 2022年5月 [査読有り]

There are concerns about the negative effects of fructose intake during pregnancy on the next generation. We have previously reported that offspring from dams fed with fructose during gestation and lactation demonstrate abnormal lipid metabolism i...

DNA methylation level of the gene encoding thioredoxin-interacting protein in peripheral blood cells is associated with metabolic syndrome in the Japanese general population.

Mirai Yamazaki Hiroya Yamada Eiji Munetsuna Keisuke Maeda Yoshitaka Ando Genki Mizuno Ryosuke Fujii Yoshiki Tsuboi Koji Ohashi Hiroaki Ishikawa Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

Endocrine journal 69(3) 319-326 2022年3月 [査読有り]

Metabolic syndrome (MetS) is cluster of metabolic diseases, including abdominal obesity, hyperglycemia, high blood pressure, and dyslipidemia, that directly escalate the risk of type 2 diabetes, heart disease, and stroke. Thioredoxin-interacting p...

Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence.

Itsuki Kageyama Hiroya Yamada Eiji Munetsuna Mirai Yamazaki Yoshitaka Ando Genki Mizuno Ryosuke Fujii Yuki Nouchi Takuya Wakasugi Tomohide Sakakibara Atsushi Teshigawara Hiroaki Ishikawa Yohei Shimono Koji Suzuki Shuji Hashimoto Koji Ohashi

PloS one 17(6) e0270144 2022年 [査読有り]

Consumption of fructose-containing beverages such as high-fructose corn syrup (HFCS) is increasing, raising concerns about the negative effects of excessive fructose intake. A recent report indicated that excess HFCS intake impairs hippocampal fun...