研究者氏名	山崎未来

URL
所属	藤田医科大学
部署	医学部医学科衛生学
職名	講師
学位	博士(医療科学)
J-Global ID	201901005807798674

研究分野

ライフサイエンス / 栄養学、健康科学 /
ライフサイエンス / 代謝、内分泌学 /
ライフサイエンス / 分子生物学 /

経歴

2023年10月

現在

藤田医科大学医学部医学科衛生学講師

2023年4月

2023年9月

香川県立保健医療大学保健医療学部臨床検査学科講師

2019年4月

2023年3月

香川県立保健医療大学保健医療学部臨床検査学科助教

2017年4月

2019年3月

藤田医科大学大学院保健学研究科日本学術振興会特別研究員DC2

論文

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Association between the Extent of Peripheral Blood DNA Methylation of HIF3A and Accumulation of Adiposity in community-dwelling Women: The Yakumo Study.

Genki Mizuno Hiroya Yamada Eiji Munetsuna Mirai Yamazaki Yoshitaka Ando Ryosuke Fujii Yoshiki Tsuboi Atsushi Teshigawara Itsuki Kageyama Keisuke Osakabe Keiko Sugimoto Hiroaki Ishikawa Naohiro Ichino Yoshiji Ohta Koji Ohashi Shuji Hashimoto Koji Suzuki

Endocrine research 47(3-4) 130-137 2022年 [査読有り]

INTRODUCTION: DNA methylation in the CpG sites of intron 1 of HIF3A is associated with body mass index (BMI). This cross-sectional study investigated correlations between DNA methylation of HIF3A and BMI or adiposity parameters in the Japanese pop...

Maternal fructose intake predisposes rat offspring to metabolic disorders via abnormal hepatic programming.

Eiji Munetsuna Hiroya Yamada Mirai Yamazaki Yoshitaka Ando Genki Mizuno Yuji Hattori Itsuki Kageyama Atsushi Teshigawara Yuki Nouchi Hiroaki Ishikawa Ryosuke Fujii Yoshiji Ohta Koji Suzuki Yohei Shimono Koji Ohashi Shuji Hashimoto

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35(12) e22030 2021年12月 [査読有り]

Given that fructose consumption has increased by more than 10-fold in recent decades, it is possible that excess maternal fructose consumption causes harmful effects in the next generation. This study attempted to elucidate the mechanism of the ha...

Association between circulating microRNAs and changes in kidney function: A five-year prospective study among Japanese adults without CKD.

Ryosuke Fujii Hiroya Yamada Yoshiki Tsuboi Yoshitaka Ando Eiji Munetsuna Mirai Yamazaki Koji Ohashi Hiroaki Ishikawa Yuya Ishihara Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

Clinica chimica acta; international journal of clinical chemistry 521 97-103 2021年10月 [査読有り]

BACKGROUND: Although a number of microRNAs (miRNA) reflecting kidney function has been identified, prospective studies are now urgently needed to determine a clinical utility of these miRNAs among general populations. The purpose of this study was...

Global DNA hypermethylation in peripheral blood mononuclear cells and cardiovascular disease risk: a population-based propensity score-matched cohort study.

Yoshiki Tsuboi Hiroya Yamada Eiji Munetsuna Ryosuke Fujii Mirai Yamazaki Yoshitaka Ando Genki Mizuno Hiroaki Ishikawa Koji Ohashi Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

Journal of epidemiology and community health 75(9) 890-895 2021年9月 [査読有り]

BACKGROUND: DNA methylation plays an important role in the pathogenesis and progression of cardiovascular disease (CVD) but the prospective association of DNA methylation with CVD has not been evaluated. Here, we conducted a prospective study to e...

Maternal fructose consumption downregulates hippocampal catalase expression via DNA methylation in rat offspring.

Genki Mizuno Eiji Munetsuna Hiroya Yamada Mirai Yamazaki Yoshitaka Ando Yuji Hattori Itsuki Kageyama Atsushi Teshigawara Yuki Nouchi Ryosuke Fujii Hiroaki Ishikawa Koji Suzuki Shuji Hashimoto Koji Ohashi Yohei Shimono

Nutrition research (New York, N.Y.) 92 40-48 2021年8月 [査読有り]

Some studies have demonstrated that excessive fructose consumption negatively impact brain function. Recently, the Developmental Origins of Health and Disease hypothesis - which suggests that maternal nutritional status during gestation and lactat...