Journal of psychopharmacology (Oxford, England) 36(9) 2698811221112937-2698811221112937 2022年7月
BACKGROUND: Although clozapine-induced granulocytopenia (CIG) is less severe than clozapine-induced agranulocytosis (CIA), and some patients with CIG may not go on to develop serious complications, clozapine is discontinued in cases of both CIA an...
Rei Aoki Takeo Saito Kohei Ninomiya Ayu Shimasaki Takuma Ashizawa Kenta Ito Masashi Ikeda Nakao Iwata
Psychiatry and clinical neurosciences 76(8) 361-366 2022年5月
AIM: The genetic relationship between schizophrenia (SCZ) and other nonpsychiatric disorders remains largely unknown. We examined the shared genetic components between these disorders based on multipopulation data sets. METHODS: We used two data s...
Yunfeng Ruan Yen-Feng Lin Yen-Chen Anne Feng Chia-Yen Chen Max Lam Zhenglin Guo Yong Min Ahn Kazufumi Akiyama Makoto Arai Ji Hyun Baek Wei J. Chen Young-Chul Chung Gang Feng Kumiko Fujii Stephen J. Glatt Kyooseob Ha Kotaro Hattori Teruhiko Higuchi Akitoyo Hishimoto Kyung Sue Hong Yasue Horiuchi Hai-Gwo Hwu Masashi Ikeda Sayuri Ishiwata Masanari Itokawa Nakao Iwata Eun-Jeong Joo Rene S. Kahn Sung-Wan Kim Se Joo Kim Se Hyun Kim Makoto Kinoshita Hiroshi Kunugi Agung Kusumawardhani Jimmy Lee Byung Dae Lee Heon-Jeong Lee Jianjun Liu Ruize Liu Xiancang Ma Woojae Myung Shusuke Numata Tetsuro Ohmori Ikuo Otsuka Yuji Ozeki Sibylle G. Schwab Wenzhao Shi Kazutaka Shimoda Kang Sim Ichiro Sora Jinsong Tang Tomoko Toyota Ming Tsuang Dieter B. Wildenauer Hong-Hee Won Takeo Yoshikawa Alice Zheng Feng Zhu Lin He Akira Sawa Alicia R. Martin Shengying Qin Hailiang Huang Tian Ge
Nature Genetics 54(5) 573-580 2022年5月 [査読有り]
Polygenic risk scores (PRS) have attenuated cross-population predictive performance. As existing genome-wide association studies (GWAS) have been conducted predominantly in individuals of European descent, the limited transferability of PRS reduce...
The amygdala is a prominent region of the brain that plays a critical role in the pathophysiology of major depressive disorder (MDD). The amygdala is formed from a collection of interconnected substructures (nuclei) that relay signals from multipl...
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