Immunopharmacology and immunotoxicology 31(1) 103-7 2009年
The effect of lectins on the formation of osteoclasts in RAW 264.7 mouse macrophage cells was examined. Concanavalin A (Con A) induced the formation of multinucleated giant cells (MGC) whereas pokeweed mitogen and phytohemagglutinin did not do it....
Ferdaus Hassan Shamima Islam Gantsetseg Tumurkhuu Jargalsaikhan Dagvadorj Yoshikazu Naiki Takayuki Komatsu Naoki Koide Tomoaki Yoshida Takashi Yokochi
Cellular immunology 256(1-2) 99-103 2009年 [査読有り]
The effect of toll-like receptor (TLR) 7 ligand pretreatment on the production of tumor necrosis factor (TNF)-alpha in response to TLR7 or TLR2 ligand was examined in order to establish a new TLR-mediated tolerance. RAW 264.7 macrophage-like cells...
Shamima Islam Ferdaus Hassan Gantsetseg Tumurkhuu Jargalsaikhan Dagvadorj Naoki Koide Yoshikazu Naiki Tomoaki Yoshida Takashi Yokochi
Microbiology and immunology 52(12) 585-90 2008年12月 [査読有り]
RAW 264.7 macrophage cells differentiate into osteoclast-like cells in the presence of RANKL. Participation of M-CSF in RANKL-induced osteoclast formation of RAW 264.7 cells was examined. TRAP-positive osteoclast-like cells appeared in RAW 264.7 c...
Abu Shadat M Noman Naoki Koide Imtiaz I-E Khuda Jargalsaikhan Dagvadorj Gantsetseg Tumurkhuu Yoshikazu Naiki Takayuki Komatsu Tomoaki Yoshida Takashi Yokochi
Biochemical and biophysical research communications 374(4) 683-7 2008年10月
The effect of thalidomide on epidermal growth factor (EGF)-induced cell growth was examined. Thalidomide inhibited EGF-induced cell growth in mouse and human monocytic leukemia cells, RAW 264.7, U937 and THP-1. Thalidomide inhibited EGF-induced ph...
G. Tumurkhuu N. Koide J. Dagvadorj A. Morikawa F. Hassan S. Islam Y. Naiki I. Mori T. Yoshida T. Yokochi
CLINICAL AND EXPERIMENTAL IMMUNOLOGY 152(1) 182-191 2008年4月 [査読有り]
The mechanism underlying acute lung injury in lethal endotoxic shock induced by administration of lipopolysaccharide (LPS) into alpha-galactosylceramide (alpha-GalCer)-sensitized mice was studied. Sensitization with alpha-GalCer resulted in the in...
The effect of lipopolysaccharide (LPS) on valproic acid (VPA)-induced cell death was examined by using mouse RAW 264.7 macrophage cells. LPS inhibited the activation of caspase 3 and poly (ADP-ribose) polymerase and prevented VPA-induced apoptosis...
Naoki Koide Yoshikazu Naiki Erdenezaya Odkhuu Bilegtsaikhan Tsolmongyn Takayuki Komatsu Kiyoaki Ito Tomoaki Yoshida Takashi Yokochi
Oncology research 21(1) 59-65 2013年 [査読有り]
A toll-like receptor 4 (TLR-4) ligand, lipopolysaccharide (LPS) not only activates expression and secretion of inflammatory cytokines, but it also often shows toxicity in monocytes. Whether an oncogenic protein, β-catenin, is positively involved i...
The LPS-mediated lethality of NC/Nga mice, having fewer NKT cells, was examined by using d-galactosamine (d-GalN)-sensitization. The NC/Nga mice were not killed by a simultaneous administration of d-GalN and LPS whereas all C57BL/6 (B6) control mi...
Thalidomide is known as an anti-angiogenic, anti-tumor, and anti-proliferative agent, widely used in the treatment of some immunological disorders and cancers. The effect of thalidomide on interferon (IFN)-gamma induced nitric oxide (NO) productio...
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