Jargalsaikhan Dagvadorj   Yoshikazu Naiki   Gantsetseg Tumurkhuu   Ferdaus Hassan   Shamima Islam   Naoki Koide   Isamu Mori   Tomoaki Yoshida   Takashi Yokochi   
Innate immunity 14(2) 109-15 2008年4月
The mechanism of interleukin (IL)-10-mediated inhibition of tumor necrosis factor (TNF)-alpha production was studied by lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells. IL-10 inhibited TNF-alpha production transiently at an early st...
F. Hassan   A. Morikawa   S. Islam   G. Tumurkhuu   J. Dagvadorj   N. Koide   Y. Naiki   I. Mori   T. Yoshida   T. Yokochi   
CLINICAL AND EXPERIMENTAL IMMUNOLOGY 151(2) 334-340 2008年2月 [査読有り]
The effect of lipopolysaccharide (LPS) on the in vivo lethal action of doxorubicin (DOX) against mice was studied. DOX killed LPS-pretreated mice much earlier than untreated mice, and exhibited a stronger toxic action against LPS-pretreated mice. ...
N. Koide   A. Morikawa   G. Tumurkhuu   J. Dagvadorj   F. Hassan   S. Islam   Y. Naiki   I. Mori   T. Yoshida   T. Yokochi   
CLINICAL AND EXPERIMENTAL IMMUNOLOGY 150(3) 553-560 2007年12月 [査読有り]
The effect of interferon (IFN)-gamma and/or lipopolysaccharide (LPS) on Fas-mediated cell death with anti-Fas agonistic antibody in vascular endothelial cells was examined using a mouse END-D cell line. Anti-Fas agonistic antibody exhibited cytoto...
Shamima Islam   Ferdaus Hassan   Gantsetseg Tumurkhuu   Jargalsaikhan Dagvadorj   Naoki Koide   Yoshikazu Naiki   Isamu Mori   Tomoaki Yoshida   Takashi Yokochi   
Biochemical and biophysical research communications 360(2) 346-51 2007年8月 [査読有り]
Lipopolysaccharide (LPS) is a potent bone resorbing factor. The effect of LPS on osteoclast formation was examined by using murine RAW 264.7 macrophage cells. LPS-induced the formation of multinucleated giant cells (MGC) in RAW 264.7 cells 3 days ...
Gantsetseg Tumurkhuu   Naoki Koide   Jargalsaikhan Dagvadorj   Ferdaus Hassan   Shamima Islam   Yoshikazu Naiki   Isamu Mori   Tomoaki Yoshida   Takashi Yokochi   
FEMS immunology and medical microbiology 49(2) 304-11 2007年3月
Antioxidants are able to inhibit inflammatory gene expression in response to lipopolysaccharide via down-regulating generation of intracellular reactive oxygen species (ROS) as second messengers. The effect of manganese (III) tetrakis (4-benzoic a...
The effect of lipopolysaccharide (LPS) on valproic acid (VPA)-induced cell death was examined by using mouse RAW 264.7 macrophage cells. LPS inhibited the activation of caspase 3 and poly (ADP-ribose) polymerase and prevented VPA-induced apoptosis...
Naoki Koide   Yoshikazu Naiki   Erdenezaya Odkhuu   Bilegtsaikhan Tsolmongyn   Takayuki Komatsu   Kiyoaki Ito   Tomoaki Yoshida   Takashi Yokochi   
Oncology research 21(1) 59-65 2013年 [査読有り]
A toll-like receptor 4 (TLR-4) ligand, lipopolysaccharide (LPS) not only activates expression and secretion of inflammatory cytokines, but it also often shows toxicity in monocytes. Whether an oncogenic protein, β-catenin, is positively involved i...
The LPS-mediated lethality of NC/Nga mice, having fewer NKT cells, was examined by using d-galactosamine (d-GalN)-sensitization. The NC/Nga mice were not killed by a simultaneous administration of d-GalN and LPS whereas all C57BL/6 (B6) control mi...
Thalidomide is known as an anti-angiogenic, anti-tumor, and anti-proliferative agent, widely used in the treatment of some immunological disorders and cancers. The effect of thalidomide on interferon (IFN)-gamma induced nitric oxide (NO) productio...