Shamima Islam   Ferdaus Hassan   Gantsetseg Tumurkhuu   Hiroyasu Ito   Naoki Koide   Isamu Mori   Tomoaki Yoshida   Takashi Yokochi   
CANCER CHEMOTHERAPY AND PHARMACOLOGY 59(2) 227-233 2007年2月 [査読有り]
The effect of 5-fluorouracil (5-FU) on the production of nitric oxide ( NO) in macrophages was examined by using lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. 5-FU at non-toxic concentrations significantly inhibited NO production in LPS-sti...
Naoki Koide   Mya Mya Mu   Ferdaus Hassan   Shamima Islam   Gantsetseg Tumurkhuu   Jargalsaikhan Dagvadorj   Yoshikazu Naiki   Isamu Mori   Tomoaki Yoshida   Takashi Yokochi   
Journal of endotoxin research 13(3) 167-75 2007年
Lipopolysaccharide (LPS) enhances the production of nitric oxide (NO) in interferon (IFN)-gamma-stimulated vascular endothelial cells. We studied the mechanism by which LPS enhances IFN-gamma-induced NO production by using the murine vascular endo...
Ferdaus Hassan   Shamima Islam   Gantsetseg Tumurkhuu   Yoshikazu Naiki   Naoki Koide   Isamu Mori   Tomoaki Yoshida   Takashi Yokochi   
BMC cancer 6 281-281 2006年12月
BACKGROUND: Recently it has been reported that, toll-like receptors (TLRs) are expressed on a series of tumor cells, such as colon cancer, breast cancer, prostate cancer, melanoma and lung cancer. Although some cancer cells like melanoma cells are...
Many studies indicate that Chlamydia pneumoniae infection is a crucial risk factor in atherogenesis. The most relevant cell type for the pathogenesis is the macrophage, which possesses classical scavenger receptors that uptake oxidized low-density...
Gantsetseg Tumurkhuu   Naoki Koide   Kazuko Takahashi   Ferdaus Hassan   Shamima Islam   Hiroyasu Ito   Isamu Mori   Tomoaki Yoshida   Takashi Yokochi   
MICROBIOLOGY AND IMMUNOLOGY 50(6) 421-427 2006年 [査読有り]
Biological activities of lipopolysaccharide (LPS) from Brucella melitensis 16M were characterized in comparison with LPS from Escherichia coli O55. LPS extracted from B. melitensis was smooth type by electrophoretic analysis with silver staining. ...
The effect of lipopolysaccharide (LPS) on valproic acid (VPA)-induced cell death was examined by using mouse RAW 264.7 macrophage cells. LPS inhibited the activation of caspase 3 and poly (ADP-ribose) polymerase and prevented VPA-induced apoptosis...
Naoki Koide   Yoshikazu Naiki   Erdenezaya Odkhuu   Bilegtsaikhan Tsolmongyn   Takayuki Komatsu   Kiyoaki Ito   Tomoaki Yoshida   Takashi Yokochi   
Oncology research 21(1) 59-65 2013年 [査読有り]
A toll-like receptor 4 (TLR-4) ligand, lipopolysaccharide (LPS) not only activates expression and secretion of inflammatory cytokines, but it also often shows toxicity in monocytes. Whether an oncogenic protein, β-catenin, is positively involved i...
The LPS-mediated lethality of NC/Nga mice, having fewer NKT cells, was examined by using d-galactosamine (d-GalN)-sensitization. The NC/Nga mice were not killed by a simultaneous administration of d-GalN and LPS whereas all C57BL/6 (B6) control mi...
Thalidomide is known as an anti-angiogenic, anti-tumor, and anti-proliferative agent, widely used in the treatment of some immunological disorders and cancers. The effect of thalidomide on interferon (IFN)-gamma induced nitric oxide (NO) productio...