Naoki Koide Akiko Morikawa Hiroyasu Ito Tsuyoshi Sugiyama Ferdaus Hassan Shamima Islam Gantsetseg Tumurkhuu Isamu Mori Tomoaki Yoshida Takashi Yokochi
Journal of endotoxin research 12(6) 346-51 2006年 [査読有り]
Previously, we found that mouse TH2.52 cells possess the characteristic of CD5(+) B1 cells and proliferate in response to lipopolysaccharide (LPS). The effect of LPS on cytokine production by TH2.52 B1 cells was studied. TH2.52 cells constitutivel...
N Koide H Ito MM Mu T Sugiyama F Hassan S Islam Mori, I T Yoshida T Yokochi
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY 45(2) 213-219 2005年8月 [査読有り]
The present study was conducted to determine effects of 00126, a specific inhibitor of mitogen-activated kinase kinase 1/2, on production of nitric oxide (NO) in RAW264.7 macrophage cells. 00126 significantly enhanced NO production in lipopolysacc...
Amaylia Oehadian Naoki Koide Mya Mya Mu Ferdaus Hassan Shamima Islam Tomoaki Yoshida Takashi Yokochi
Cancer letters 225(1) 85-92 2005年7月 [査読有り]
The effect of interferon (IFN)-alpha, beta and gamma on the growth of DHL-4 diffuse large B cell lymphoma cells was studied. IFN-beta significantly inhibited the cell growth, and the effect was stronger than that of IFN-alpha. IFN-gamma did not in...
MM Mu N Koide F Hassan S Islam T Sugiyama H Ito Mori, I T Yoshida T Yokochi
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY 43(2) 277-286 2005年2月 [査読有り]
The effect of inhibition of mitogen and stress-activated protein kinases 1/2 (MSK1/2) on lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells was investigated. Pretreatment with Ro 31-8220, an inhibitor of MSK1/2, induced cell death in L...
Amaylia Oehadian Naoki Koide Mya Mya Mu Ferdaus Hassan Tomoaki Yoshida Takashi Yokochi
Haematologica 90(2) 272-3 2005年2月 [査読有り]
A new method, combining seminested polymerase chain reaction (PCR) with heteroduplex analysis, was utilized to detect follicular lymphoma (FL) cells in peripheral blood. The method, based on the detection of IgH rearrangements in DNA, detected the...
The effect of lipopolysaccharide (LPS) on valproic acid (VPA)-induced cell death was examined by using mouse RAW 264.7 macrophage cells. LPS inhibited the activation of caspase 3 and poly (ADP-ribose) polymerase and prevented VPA-induced apoptosis...
Naoki Koide Yoshikazu Naiki Erdenezaya Odkhuu Bilegtsaikhan Tsolmongyn Takayuki Komatsu Kiyoaki Ito Tomoaki Yoshida Takashi Yokochi
Oncology research 21(1) 59-65 2013年 [査読有り]
A toll-like receptor 4 (TLR-4) ligand, lipopolysaccharide (LPS) not only activates expression and secretion of inflammatory cytokines, but it also often shows toxicity in monocytes. Whether an oncogenic protein, β-catenin, is positively involved i...
The LPS-mediated lethality of NC/Nga mice, having fewer NKT cells, was examined by using d-galactosamine (d-GalN)-sensitization. The NC/Nga mice were not killed by a simultaneous administration of d-GalN and LPS whereas all C57BL/6 (B6) control mi...
Thalidomide is known as an anti-angiogenic, anti-tumor, and anti-proliferative agent, widely used in the treatment of some immunological disorders and cancers. The effect of thalidomide on interferon (IFN)-gamma induced nitric oxide (NO) productio...
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