T Matsui J Hamako T Matsushita T Nakayama Y Fujimura K Titani
BIOCHEMISTRY 41(25) 7939-7946 2002年6月 [査読有り]
Bitiscetin, a C-type lectin-like heterodimeric snake venom protein purified from Bitis arietans, binds to human von Willebrand factor (VWF) and induces the platelet membrane glycoprotein (GP) lb-dependent platelet agglutination in vitro similar to...
S Hirotsu H Mizuno K Fukuda MC Qi T Matsui J Hamako T Morita K Titani
BIOCHEMISTRY 40(45) 13592-13597 2001年11月 [査読有り]
Bitiscetin, a C-type lectin-like protein isolated from the venom of the snake Bitis arientans, promotes the interactions between plasma von Willebrand factor (VWF) and platelet membrane glycoprotein Ib (GPIb) to induce platelet aggregation. We rep...
M Ito J Hamako Y Sakurai M Matsumoto Y Fujimura M Suzuki K Hashimoto K Titani T Matsui
BIOCHEMISTRY 40(14) 4503-4511 2001年4月 [査読有り]
The primary structure of kaouthiagin, a metalloproteinase from the venom of the cobra snake Naja kaouthia which specifically cleaves human von Willebrand factor (VWF), was determined by amino acid sequencing. Kaouthiagin is composed of 401 amino a...
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1525(1-2) 50-57 2001年2月
Binding specificities of ABO blood group-recognizing lectins toward blood group antigens on neoglycoproteins, glycoproteins and complex-type oligosaccharides were studied by lectin-blotting analysis, enzyme linked immunosorbent assay and lectin-co...
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医療科学部