JOURNAL OF GENERAL VIROLOGY 92(Pt 12) 2914-2921 2011年12月 [査読有り]
The infectivity of rotavirus (RV) is dependent on an activation process triggered by the proteolytic cleavage of its spike protein VP4. This activation cleavage is performed by exogenous trypsin in the lumen of the intestines in vivo. Here, we rep...
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 134(7) 789-792 2008年7月 [査読有り]
Purpose To confirm the presence of the susceptible gene for the thymoma development in the region that was assumed by the previous linkage study by Oyabu et al. (J Natl Cancer Inst 91:279-282, 1999), we tried to establish a congenic strain of rats...
N Monnier   K Higo-Moriguchi   ZYJ Sun   BVV Prasad   K Taniguchi   PR Dormitzer   
JOURNAL OF VIROLOGY 80(3) 1513-1523 2006年2月 [査読有り]
The most intensively studied rotavirus strains initially attach to cells when the "heads" of their protruding spikes bind cell surface sialic acid. Rotavirus strains that cause disease in humans do not bind this ligand. The structure of the sialic...
K Higo-Moriguchi   Y Akahori   Y Iba   Y Kurosawa   K Taniguchi   
JOURNAL OF VIROLOGY 78(7) 3325-3332 2004年4月 [査読有り]
A human antibody library constructed by utilizing a phage display system was used for the isolation of human antibodies with neutralizing activity specific for human rotavirus. In the library, the Fab form of an antibody fused to truncated cp3 is ...
Rahaman S   Higo-Moriguchi K   Htun K W   Taniguchi K   Icatlio FC   Tsuji T   Kodama Y   Nguyen SV   Umeda K   Oo HN   Myint YY   Htut T   Myint SS   Thura K   Thu HM   Fatmawati NND   Ogyma K   
46th Joint Working Conference on Viral Diseases, The Japan-United States Cooperative Medical Science Program 2012年