NEUROSCIENCE RESEARCH 35(4) 253-263 1999年12月 [査読有り]
Mechanisms underlying suppression of T- and L-type Ca2+ currents (I-Ca,I-T and I-Ca,I-L) by odorants were investigated in newt olfactory receptor cells (ORCs) using the whole-cell version of the patch-clamp technique. Under voltage clamp, odorants...
The kinetics of glutamate concentration in the synaptic cleft is an important determinant of synaptic function. To elucidate peak concentration of glutamate released from a single vesicle in the cleft, spontaneous excitatory postsynaptic currents ...
Effects of odorants on a delayed rectifier potassium current (IK) in newt olfactory receptor cells (ORCs) were investigated using the whole-cell version of the patch-clamp technique. Under voltage clamp, odorants (amyl acetate, limonene and acetop...
JOURNAL OF NEUROSCIENCE 19(8) 2954-2959 1999年4月 [査読有り]
The AMPA receptor, ubiquitous in brain, is termed "ionotropic" because it gates an ion channel directly. We found that an AMPA receptor can also modulate a G-protein to gate an ion channel indirectly. Glutamate applied to a retinal ganglion cell b...
F Kawai   T Kurahashi   A Kaneko   
NATURE NEUROSCIENCE 2(2) 133-138 1999年2月 [査読有り]
Olfactory perception is influenced by hormones. Here we report that adrenaline can directly affect the signal encoding of olfactory receptor cells. Application of adrenaline suppressed action potentials near threshold and increased their frequency...