研究者氏名	安岡秀剛
	ヤスオカヒデカタ
URL
所属	藤田医科大学
部署	医学部・リウマチ・膠原病内科学
職名	教授
学位	博士（医学）(慶應義塾大学)
J-Global ID	200901028124352037

研究キーワード

アレルギー性疾患 ,免疫性疾患 ,allergic diseases ,Immunologic diseases

研究分野

ライフサイエンス / 膠原病、アレルギー内科学 /
ライフサイエンス / 免疫学 /

経歴

藤田医科大学医学部リウマチ・膠原病内科学教授

学歴

2003年

慶應義塾大学大学院医学研究科内科学専攻（リウマチ）

2003年

慶應義塾大学

1997年

慶應義塾大学医学部医学科

1997年

慶應義塾大学

論文

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Intravenous epoprostenol treatment of patients with connective tissue disease and pulmonary arterial hypertension at a single center

Yuichiro Shirai Hidekata Yasuoka Tsutomu Takeuchi Toru Satoh Masataka Kuwana

Modern Rheumatology 23(6) 1211-1220 2013年11月 [査読有り]

Objective: To assess the efficacy of epoprostenol treatment in Japanese patients with pulmonary arterial hypertension (PAH) associated with connective tissue disease (CTD). Methods: Sixteen patients with PAH-CTD treated with continuous intravenous...

Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis

Keiko Aida-Yasuoka Christine Peoples Hidekata Yasuoka Pamela Hershberger Katelynn Thiel Jane A. Cauley Thomas A. Medsger Carol A. Feghali-Bostwick

ARTHRITIS RESEARCH & THERAPY 15(1) R10 2013年 [査読有り]

Introduction: Systemic sclerosis (SSc) is more prevalent in women. Our goal is to determine the effects of 17 beta-estradiol (E2) on the development of fibrosis and to compare circulating levels of estrogens in SSc patients and healthy controls.
M...

Versican is upregulated in circulating monocytes in patients with systemic sclerosis and amplifies a CCL2-mediated pathogenic loop

Ayako Masuda Hidekata Yasuoka Takashi Satoh Yuka Okazaki Yukie Yamaguchi Masataka Kuwana

ARTHRITIS RESEARCH & THERAPY 15(4) R74 2013年 [査読有り]

Introduction: Altered phenotypes of circulating monocytes of patients with systemic sclerosis (SSc) have been reported, but the role of these alterations in the pathogenesis of SSc remains unclear. This study was undertaken to identify molecules t...

Clinical characteristics and survival of Japanese patients with connective tissue disease and pulmonary arterial hypertension: a single-centre cohort

Yuichiro Shirai Hidekata Yasuoka Yutaka Okano Tsutomu Takeuchi Toru Satoh Masataka Kuwana

RHEUMATOLOGY 51(10) 1846-1854 2012年10月 [査読有り]

Objective. To clarify the characteristics, survival and predictors of mortality in Japanese patients with pulmonary arterial hypertension (PAH) associated with CTD.
Methods. This single-centre cohort study enrolled 70 consecutive patients with PAH...

Decreased caveolin-1 levels contribute to fibrosis and deposition of extracellular IGFBP-5

Yukie Yamaguchi Hidekata Yasuoka Donna B. Stolz Carol A. Feghali-Bostwick

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 15(4) 957-969 2011年4月 [査読有り]

Our previous studies have demonstrated increased expression of insulin-like growth factor binding protein-5 (IGFBP-5) in fibrotic tissues and IGFBP-5 induction of extracellular matrix (ECM) components. The mechanism resulting in increased IGFBP-5 ...

MISC

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Autoreactive CD8+ cytotoxic T lymphocytes to major histocompatibility complex class I chain-related gene A in patients with Behçet's disease

Hidekata Yasuoka Yuka Okazaki Yutaka Kawakami Michito Hirakata Hidetoshi Inoko Yasuo Ikeda Masataka Kuwana

Arthritis and Rheumatism 50(11) 3658-3662 2004年11月

Objective. To detect and characterize the autoreactive CD8+ T cells to major histocompatibility complex class 1 chain-related gene A (MICA), a stress-inducible antigen preferentially expressed on the epithelium and endothelium, in patients with Be...

Autoreactive CD8+ cytotoxic T lymphocytes to major histocompatibility complex class I chain-related gene A in patients with Behcet's disease

H Yasuoka Y Okazaki Y Kawakami M Hirakata H Inoko Y Ikeda M Kuwana

ARTHRITIS AND RHEUMATISM 50(11) 3658-3662 2004年11月

Objective. To detect and characterize the autoreactive CD8+ T cells to major histocompatibility complex class I chain-related gene A (MICA), a stress-inducible antigen preferentially expressed on the epithelium and endothelium, in patients with Be...

Single nucleotide polymorphisms of the inflammatory cytokine genes in adults with chronic immune thrombocytopenic purpura

T Satoh JP Pandey Y Okazaki H Yasuoka Y Kawakami Y Ikeda M Kuwana

BRITISH JOURNAL OF HAEMATOLOGY 124(6) 796-801 2004年3月

Single nucleotide polymorphisms (SNPs) of inflammatory cytokine genes were examined in 84 adult Japanese patients with chronic immune thrombocytopenic purpura (ITP) and 56 race-matched healthy controls. The SNPs examined were within the genes enco...

多発性筋炎・皮膚筋炎(PM/DM)の新たな自己抗体Profileに関する研究

第48回日本リウマチ学会総会 2004年

赤芽球癆を合併した抗Ku抗体陽性の全身性エリテマトーデス(SLE)の一例

第48回日本リウマチ学会総会 2004年