PURPOSE: Patients with complete achromatopsia (ACHM) lack cone function, and patients with incomplete ACHM have relatively good visual acuity with residual color vision. The pathological mechanism(s) underlying incomplete ACHM has not been determi...

Short-term focal macular electroretinogram of eyes treated by aflibercept & photodynamic therapy for polypoidal choroidal vasculopathy

Kei Takayama Hiroki Kaneko Keiko Kataoka Shinji Ueno Piao Chang-Hua Yasuki Ito Hiroko Terasaki

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 255(3) 449-455 2017年3月 [査読有り]

To compare short-term outcomes of intravitreal aflibercept injection (IAI) with or without initial photodynamic therapy (PDT) for polypoidal choroidal vasculopathy (PCV) using focal macular electroretinography (FMERG).
Observation case series.
Twe...

Better Visual Outcome by Intraocular Lens Ejection in Geriatric Patients with Ruptured Ocular Injuries.

Hiroki Kaneko Tetsu Asami Tadasu Sugita Taichi Tsunekawa Toshiyuki Matsuura Kei Takayama Kentaro Yamamoto Shu Kachi Yasuki Ito Shinji Ueno Norie Nonobe Keiko Kataoka Ayana Suzumura Takeshi Iwase Hiroko Terasaki

PloS one 12(1) e0170094 2017年

Ocular trauma is one of the leading causes of visual impairment worldwide. Because of the popularity of cataract surgeries, aged individuals with ocular trauma commonly have a surgical wound in their eyes. The purpose of this study was to evaluate...

In vivo imaging of a cone mosaic in a patient with achromatopsia associated with a GNAT2 variant.

Shinji Ueno Ayami Nakanishi Taro Kominami Yasuki Ito Takaaki Hayashi Kazutoshi Yoshitake Yuichi Kawamura Kazushige Tsunoda Takeshi Iwata Hiroko Terasaki

Japanese journal of ophthalmology 61(1) 92-98 2017年1月

PURPOSE: The 2 most common causative genes for achromatopsia (ACHM) are CNGA3 and CNGB3; other genes including GNAT2 account for only a small portion of ACHM cases. The cone mosaics in eyes with CNGA3 and CNGB3 variants are severely disrupted; the...

Correlation between miR-148 Expression in Vitreous and Severity of Rhegmatogenous Retinal Detachment.

Taichi Tsunekawa Hiroki Kaneko Kei Takayama Shiang-Jyi Hwang Akio Oishi Yosuke Nagasaka Fuxiang Ye Takeshi Iwase Norie Nonobe Shinji Ueno Yasuki Ito Shunsuke Yasuda Toshiyuki Matsuura Hideyuki Shimizu Ayana Suzumura Keiko Kataoka Hiroko Terasaki

BioMed research international 2017 3427319-3427319 2017年

Purpose. We had earlier reported positive hsa-miR-148a-3p expression in eyes with rhegmatogenous retinal detachment (RRD) and its involvement in the epithelial-mesenchymal transition of retinal pigment epithelium in vitro. Here we investigated the...

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Multiple Sub–Internal Limiting Membrane Hemorrhages With Double Ring Sign in Eyes With Valsalva Retinopathy

Takeshi Iwase Eimei Ra Yasuki Ito Hiroko Terasaki

Retina 38(1) E1-E2 2018年1月

Regeneration of Photoreceptor Outer Segments After Scleral Buckling Surgery for Rhegmatogenous Retinal Detachment REPLY

Eimei Ra Yasuki Ito Kenichi Kawano Takeshi Iwase Hiroki Kaneko Shinji Ueno Shunsuke Yasuda Keiko Kataoka Hiroko Terasaki

AMERICAN JOURNAL OF OPHTHALMOLOGY 180 178-179 2017年8月

Optical coherence tomography angiography in leber hereditary optic neuropathy

Kei Takayama Yasuki Ito Hiroki Kaneko Keiko Kataoka Eimei Ra Hiroko Terasaki

ACTA OPHTHALMOLOGICA 95(4) E344-E345 2017年6月 [査読有り]

Comparison between 1-year outcomes of aflibercept with and without photodynamic therapy for polypoidal choroidal vasculopathy: Retrospective observation study

Kei Takayama Hiroki Kaneko Keiko Kataoka Kyoko Hattori Eimei Ra Taichi Tsunekawa Hiroshi Fukukita Fuminori Haga Yasuki Ito Hiroko Terasaki

PLOS ONE 12(5) e0176100 2017年5月 [査読有り][招待有り]

Polypoidal choroidal vasculopathy (PCV) is characterized by polyp-like choroidal neovascularization and a branching vascular network. Intravitreal aflibercept injection (IAI) or photodynamic therapy (PDT) is used for treatment. We retrospectively ...

Nutritional Supplementation Inhibits the Increase in Serum Malondialdehyde in Patients with Wet Age-Related Macular Degeneration

Toshiyuki Matsuura Kei Takayama Hiroki Kaneko Fuxiang Ye Hiroshi Fukukita Taichi Tsunekawa Keiko Kataoka Shiang-Jyi Hwang Yosuke Nagasaka Yasuki Ito Hiroko Terasaki

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 9548767 2017年 [査読有り]

Purpose. To compare serum levels of malondialdehyde (MDA) in patients with wet age-related macular degeneration (wAMD), patients with dryAMD(dAMD), and patients without AMD and to evaluate the efficacy of nutritional supplementation for treating e...

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視覚再生を目指した多角的機能構造解析アプローチ
日本学術振興会: 科学研究費助成事業
寺崎浩子伊藤逸毅上野真治

研究期間: 2019年4月 - 2022年3月

超高解像度眼底撮影装置・黄斑部局所網膜電図を用いた網膜血管と視機能の関係の検討
日本学術振興会: 科学研究費助成事業
伊藤逸毅寺崎浩子

研究期間: 2016年4月 - 2019年3月

剥離網膜の包括的病態解析と新規細胞保護治療開発
日本学術振興会: 科学研究費助成事業
寺崎浩子伊藤逸毅兼子裕規上野真治岩瀬剛

研究期間: 2015年4月 - 2018年3月

網膜静脈閉塞に伴う黄斑浮腫の機能・形態・分子生物学的解析
日本学術振興会: 科学研究費助成事業
安田俊介寺崎浩子近藤峰生伊藤逸毅加地秀浅見哲上野真治岩瀬剛兼子裕規

研究期間: 2014年4月 - 2017年3月

補償光学眼底撮影装置・黄斑部局所網膜電図を用いた網膜形態と視機能の関係の検討
日本学術振興会: 科学研究費助成事業
伊藤逸毅寺﨑浩子

研究期間: 2013年4月 - 2016年3月

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