Wenjing Li   Takashi Moriwaki   Tomomi Tani   Takashi Watanabe   Kozo Kaibuchi   Gohta Goshima   
JOURNAL OF CELL BIOLOGY 199(5) 849-862 2012年11月 [査読有り]
Dynamic microtubules (MTs) are essential for various intracellular events, such as mitosis. In Drosophila melanogaster S2 cells, three MT tip-localizing proteins, Msps/XMAP215, EB1, and Sentin (an EB1 cargo protein), have been identified as being ...
Shujie Wang   Takashi Watanabe   Kenji Matsuzawa   Akira Katsumi   Mai Kakeno   Toshinori Matsui   Feng Ye   Kazuhide Sato   Kiyoko Murase   Ikuko Sugiyama   Kazushi Kimura   Akira Mizoguchi   Mark H. Ginsberg   John G. Collard   Kozo Kaibuchi   
JOURNAL OF CELL BIOLOGY 199(2) 331-345 2012年10月 [査読有り]
Migrating cells acquire front-rear polarity with a leading edge and a trailing tail for directional movement. The Rac exchange factor Tiam1 participates in polarized cell migration with the PAR complex of PAR3, PAR6, and atypical protein kinase C....
Cell migration is a critical cellular process that determines embryonic development and the progression of human diseases. Therefore, cell- or context-specific mechanisms by which multiple promigratory proteins differentially regulate cell migrati...
Dishevelled is the common mediator of canonical and non-canonical Wnt signalling pathways, which are important for embryonic development, tissue maintenance and cancer progression. In the non-canonical Wnt signalling pathway, the Rho family of sma...