Disrupted-in-schizophrenia 1 (DISC1) is a susceptibility gene for major psychiatric disorders, including schizophrenia. DISC1 has been implicated in neurodevelopment in relation to scaffolding signal complexes. Here we used proteomic analysis to s...
HUMAN MOLECULAR GENETICS 20(23) 4666-4683 2011年12月 [査読有り]
Disrupted-In-Schizophrenia 1 (DISC1) is a promising candidate gene for susceptibility to psychiatric disorders, including schizophrenia. DISC1 appears to be involved in neurogenesis, neuronal migration, axon/dendrite formation and synapse formatio...
Dopamine (DA) type 1 receptor (D1R) signaling in the striatum presumably regulates neuronal excitability and reward-related behaviors through PKA. However, whether and how D1Rs and PKA regulate neuronal excitability and behavior remain largely unk...
Daisuke Ibi Taku Nagai Akira Nakajima Hiroyuki Mizoguchi Takahiro Kawase Daisuke Tsuboi Shin-Ichi Kano Yoshiaki Sato Masahiro Hayakawa Ulrike C. Lange David J. Adams M. Azim Surani Takaya Satoh Akira Sawa Kozo Kaibuchi Toshitaka Nabeshima Kiyofumi Yamada
GLIA 61(5) 679-693 2013年5月
Interferon-induced transmembrane protein 3 (IFITM3) plays a crucial role in the antiviral responses of Type I interferons (IFNs). The role of IFITM3 in the central nervous system (CNS) is, however, largely unknown, despite the fact that its expres...
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