日本神経精神薬理学会, JSNP Excellent Presentation Award for AsCNP,The ubiquitination of serotonin transporter in lymphoblasts derived from fluvoxamine-resistant depression patients
Yang Yang   Akihiro Mouri   Qiaohui Lu   Kazuo Kunisawa   Hisayoshi Kubota   Masaya Hasegawa   Mami Hirakawa   Yuko Mori   Zou Libo   Kuniaki Saito   Toshitaka Nabeshima   
Neurochemical Research 47(9) 2865-2879 2022年7月
Brain derived neurotrophic factor (BDNF) is one of the most abundant neurotrophic factors, and its deficits are involved in the pathogenesis of major depressive disorders (MDD). Loureirin C (Lou C) is a compound derived from red resin extracted fr...
Kazuo Kunisawa   Jiajing Shan   Qiaohui Lu   Yang Yang   Aika Kosuge   Hitomi Kurahashi   Kuniaki Saito   Libo Zou   Toshitaka Nabeshima   Akihiro Mouri   
Neurochemical Research 47(9) 2880-2889 2022年7月
Major depressive disorder (MDD) is the most prevalent and serious psychiatric disease involving inflammation. Loureirin C and Xanthoceraside are extracts of dragon's blood and Xanthoceras sorbifolia Bunge, respectively, which have neuroprotective ...
Acetylcholine is a neuromodulator critical for learning and memory. The cholinesterase inhibitor donepezil increases brain acetylcholine levels and improves Alzheimer's disease (AD)-associated learning disabilities. Acetylcholine activates striata...
Ming Tatt Lee   Akihiro Mouri   Hisayoshi Kubota   Hsin-Jung Lee   Man-Hsin Chang   Chen-Yi Wu   Daniel E. Knutson   Marko Mihovilovic   James Cook   Werner Sieghart   Toshitaka Nabeshima   Lih-Chu Chiou   
Biomedicine & Pharmacotherapy 150 113022-113022 2022年6月
GABAA receptors containing α6 subunits (α6GABAARs) in the cerebellum have -been implicated in schizophrenia. It was reported that the GABA synthesizing enzymes were downregulated whereas α6GABAARs were upregulated in postmortem cerebellar tissues ...