Goro Takami   Miyuki Ota   Akira Nakashima   Yoko S. Kaneko   Keiji Mori   Toshiharu Nagatsu   Akira Ota   
JOURNAL OF NEURAL TRANSMISSION 117(10) 1139-1153 2010年10月 [査読有り]
By converting changes in intracellular energy status to changes in cell membrane polarization, ATP-sensitive K(+) (K(ATP)) channels in hypothalamic appetite-regulating neurons play a critical role in linking neuronal electrochemical function, meta...
Because the subventricular zone (SVZ) constantly supplies newly generated neurons to the olfactory bulb (OB) along the rostral migratory stream (RMS) in adult brain, SVZ-RMS-OB axis has been thought to work as a unit. We previously reported that p...
A. Nakashima   N. Hayashi   Y. S. Kaneko   K. Mori   E. L. Sabban   Toshiharu Nagatsu   A. Ota   
JOURNAL OF NEURAL TRANSMISSION 116(11) 1355-1362 2009年11月 [査読有り]
Tyrosine hydroxylase (TH) catalyzes the conversion of l-tyrosine to l-dopa, which is the initial and rate-limiting step in the biosynthesis of catecholamines [CA; dopamine (DA), noradrenaline, and adrenaline], and plays a central role in the neuro...