Kazumasa Wakamatsu   Johannes M Dijkstra   Turid Mørkøre   Shosuke Ito   
International journal of molecular sciences 24(23) 2023年11月
Superficial discolored spots on Atlantic salmon (Salmo salar) fillets are a serious quality problem for commercial seafood farming. Previous reports have proposed that the black spots (called melanized focal changes (MFCs)) may be melanin, but no ...
Tiffany S Slater   Shosuke Ito   Kazumasa Wakamatsu   Fucheng Zhang   Peter Sjövall   Martin Jarenmark   Johan Lindgren   Maria E McNamara   
Nature communications 14(1) 5651-5651 2023年10月
Melanin pigments play a critical role in physiological processes and shaping animal behaviour. Fossil melanin is a unique resource for understanding the functional evolution of melanin but the impact of fossilisation on molecular signatures for eu...
Kazumasa Wakamatsu   Shosuke Ito   
International Journal of Molecular Sciences 24(9) 2023年5月
The melanin pigments eumelanin (EM) and pheomelanin (PM), which are dark brown to black and yellow to reddish-brown, respectively, are widely found among vertebrates. They are produced in melanocytes in the epidermis, hair follicles, the choroid, ...
Yusupova M   Zhou D   You J   Gonzalez-Guzman J   Ghanta MB   Pu H   Abdel-Malek Z   Chen Q   Gross SS   D'Orazio J   Ito S   Wakamatsu K   Harris ML   Zippin JH   
The Journal of investigative dermatology 143(10) 2019-2029 2023年5月
cAMP signaling is a well-established regulator of melanin synthesis. Two distinct cAMP signaling pathways-the transmembrane adenylyl cyclase pathway, activated primarily by the MC1R, and the soluble adenylyl cyclase (sAC) pathway-affect melanin sy...
Okamura, K   Araki, Y   Abe, Y   Wakamatsu, K   Tamiya, G   Seishima, M   Umetsu, T   Kato, A   Kawaguchi, M   Hayashi, M   Hozomi, Y   Suzuki, T   
23rd International Pigment Cell Conference. 2017年8月27日