堀口 明彦

81歳男性.発熱,黄疸の精査のため紹介となり,造影CTで遠位胆管に狭窄を認めた.ERC時に行った腫瘍生検で遠位胆管癌と診断し,膵頭十二指腸切除術を施行した.病理標本では腫瘍部位に腺癌の他,浸潤部位の免疫染色ではchromogranin A,synaptophysin及びCD56が陽性,MIB-1 index 80%と神経内分泌癌も認め,混在した腺癌成分と神経内分泌癌成分とが各々30%以上を占めており,Mixed neuroendocrine-non-neuroendocrine neopl...

Overall survival of patients with localized pancreatic ductal adenocarcinoma (PDAC) is extremely poor. Therefore, the establishment of multimodal treatment strategies is indispensable for PDAC patients because surgical treatment alone could not co...

OBJECTIVES: We evaluated the clinical outcomes of transumbilical single-incision laparoscopic appendectomy with extracorporeal hand-sewn stump closure in adults. METHODS: One-hundred-and-thirty-one consecutive adults with acute appendicitis were t...