OBJECTIVE: The JT interval of the myocardial repolarization time can be divided into Jpoint to T-peak interval (JTp) and T-peak to T-end interval (Tpe). It is well known that the JT interval is dependent on the heart rate, but little is known rega...
Restrictive cardiomyopathy (RCM) is a rare myocardial disease with an impaired diastolic function and poor prognosis. Almost all RCM patients are reported to have abnormal P-waves due to atrial overloading. This study aimed to reveal the character...
International Journal of Cardiology 323 168-174 2021年1月
BACKGROUND: T-wave inversion (TWI) is not considered useful for diagnosing pediatric arrhythmogenic right ventricular cardiomyopathy (ARVC), because right precordial TWI in ARVC resembles a normal juvenile pattern. OBJECTIVES: The aims of this stu...
JAPANESE JOURNAL OF PHYSIOLOGY 50(5) 469-477 2000年10月 [査読有り]
In the circular muscle of the guineapig gastric antrum, a decrease in the external Na+ to less than 20 mM produced depolarization of the membrane with transient prolongation of the slow wave. This was followed by a high rhythmic activity. The acti...
T Tomita   T Hata   H Tokuno   
JAPANESE JOURNAL OF PHYSIOLOGY 50(2) 191-198 2000年4月 [査読有り]
In the circular muscle of guinea-pig gastric antrum, the effects of removal and reapplication of K+ and Cl- were studied on the slow wave, which consists of the lower, first and upper, second components. The first component appeared to be triggere...
K Nishii   N Matsushita   H Sawada   H Sano   Y Noda   T Mamiya   T Nabeshima   Nagatsu, I   T Hata   K Kiuchi   H Yoshizato   K Nakashima   T Nagatsu   K Kobayashi   
JOURNAL OF NEUROSCIENCE RESEARCH 54(4) 450-464 1998年11月 [査読有り]
Mice lacking expression of tyrosine hydroxylase (TH), the first and rate-limiting enzyme of the catecholamine biosynthetic pathway, in dopaminergic neuronal cell types were generated by a transgenic rescue approach to clarify the role of dopamine ...
T Hata   M Nishimura   K Ogino   H Uchiyama   Y Watanabe   
HEART AND VESSELS 13(3) 114-121 1998年 [査読有り]
To elucidate the physiological role of phosphodiesterase (PDE) in cardiac pacemaker cells. we studied the electrophysiological effects of amrinone, an inhibitor of PDE type III, on the spontaneous action potential (AP) and membrane currents, using...