Xiaoping Sun   Jillian A Bristol   Satoko Iwahori   Stacy R Hagemeier   Qiao Meng   Elizabeth A Barlow   Joyce D Fingeroth   Vera L Tarakanova   Robert F Kalejta   Shannon C Kenney   
Journal of virology 87(18) 10126-38 2013年9月 [査読有り]
All eight human herpesviruses have a conserved herpesvirus protein kinase (CHPK) that is important for the lytic phase of the viral life cycle. In this study, we show that heat shock protein 90 (Hsp90) interacts directly with each of the eight CHP...
Expression of Epstein-Barr Virus BZLF1, a key protein initiating the switch from latent to lytic infection, is known to cause cell growth arrest by accumulating p53 and p21(WAF1/CIP1) in epithelial cells, but its molecular mechanism remains elusiv...
Journal of cell science 123(Pt 2) 225-35 2010年1月 [査読有り]
CDC6, a replication licensing protein, is partially exported to the cytoplasm in human cells through phosphorylation by Cdk during S phase, but a significant proportion remains in the nucleus. We report here that human CDC6 physically interacts wi...
The Journal of biological chemistry 284(32) 21557-68 2009年8月 [査読有り]
The Epstein-Barr virus (EBV) BMRF1 protein is an essential replication protein acting at viral replication forks as a viral DNA polymerase processivity factor, whereas the BALF2 protein is a single-stranded DNA-binding protein that also acts at re...
Satoko Iwahori   Takayuki Murata   Ayumi Kudoh   Yoshitaka Sato   Sanae Nakayama   Hiroki Isomura   Teru Kanda   Tatsuya Tsurumi   
The Journal of biological chemistry 284(28) 18923-31 2009年7月 [査読有り]
Epstein-Barr virus (EBV) productive replication occurs in an S-phase-like cellular environment with high cyclin-dependent kinase (CDK) activity. The EBV protein kinase (PK), encoded by the viral BGLF4 gene, is a Ser/Thr protein kinase, which phosp...
The Journal of general virology 85(Pt 10) 2857-2862 2004年10月 [査読有り]
The accumulation of cellular proliferating cell nuclear antigen (PCNA) in the nucleus of Sf9 cells has been shown to increase upon infection with Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV). Here, analysis by DNase I treatment...