Reverse genetics technology allows one to engineer replication-competent viruses from cloned cDNAs at will. Since the establishment of the initial reverse genetics system for species A rotaviruses (RVAs) requiring a helper virus in 2006, attempts ...
The Journal of general virology 101(8) 806-815 2020年6月 [査読有り]
Reassortment is an important mechanism in the evolution of group A rotaviruses (RVAs), yielding viruses with novel genetic and phenotypic traits. The classical methods for generating RVA reassortants with the desired genetic combinations are labor...
Microbiology and immunology 64(6) 401-406 2020年6月 [査読有り]
A reverse genetics technology is an incredibly useful technique both for a proper understanding of different aspects of virus biology and for the generation of complementary DNA (cDNA)-derived infectious viruses, which can act as safe and effectiv...
Tomoki Inagaki   Yoshitaka Sato   Jumpei Ito   Mitsuaki Takaki   Yusuke Okuno   Masahiro Yaguchi   H M Abdullah Al Masud   Takahiro Watanabe   Kei Sato   Shingo Iwami   Takayuki Murata   Hiroshi Kimura   
Frontiers in microbiology 11 575255-575255 2020年
Viral infection induces dynamic changes in transcriptional profiles. Virus-induced and antiviral responses are intertwined during the infection. Epstein-Barr virus (EBV) is a human gammaherpesvirus that provides a model of herpesvirus latency. To ...
The emergence and rapid spread of unusual DS-1-like intergenogroup reassortant rotaviruses having G1/3/8 genotypes have been recently reported from major parts of the world (Africa, Asia, Australia, Europe, and the Americas). During rotavirus surv...