Previous studies have demonstrated that the numbers of interfollicular epidermal stem cells (IFE-SCs) and dermal stem cells (DSCs) decrease with age and that this decrease is attributed to the age-related deterioration of skin homeostatic function...
Journal of dermatological science 106(3) 150-158 2022年5月
BACKGROUND: Age-related thinning and reduced cell proliferation in the human epidermis are associated with the accumulation of senescent cells and decreases in the number and function of epidermal stem cells. OBJECTIVE: This study examined the exp...
JOURNAL OF BIOSCIENCE AND BIOENGINEERING 116(3) 386-390 2013年9月 [査読有り]
To take advantage of the therapeutic potential of embryonic stem cells (ESCs), it is necessary to regulate their differentiation in response to defined factors. In this study, in order to explore novel molecules that regulate the differentiation o...
JOURNAL OF DERMATOLOGICAL SCIENCE 71(2) 122-129 2013年8月 [査読有り]
Backgroud: : More effective treatment strategies are needed for the chronic skin ulcers. Recently, it has been reported that clinical application of stem cells improve wound healing.
Objective: We aimed to determine the dynamic time-course movemen...
Embryonic stem cells (ES cells) are characterized by their pluripotency and infinite proliferation potential. Ever since ES cells were first established in 1981, there have been a growing number of studies aimed at clinical applications of ES cell...
Journal of Dermatology 40(5) 363-369 2013年5月 [査読有り]
We investigated the optimum application for evaluating skin irritation response by using samples of irritants commonly used as additives in cosmetics and other common household products. We studied 47 volunteers (16 men and 31 women). We selected ...