研究者氏名	藤井亮輔
	フジイリョウスケ
URL	https://sites.google.com/view/ryosukefujii/home
所属	藤田医科大学
部署	医療科学部
職名	講師
学位	医療技術学(名古屋大学)
その他の所属	名古屋大学大学院医学系研究科
J-Global ID	201801006809384973

研究キーワード

分子疫学 ,臨床検査学

研究分野

ライフサイエンス / 衛生学、公衆衛生学分野：実験系を含まない /

経歴

2023年4月

現在

藤田医科大学医療科学部講師

2018年4月

現在

名古屋大学大学医学系研究科客員研究員

2021年10月

2023年9月

Eurac Research Senior researcher

2018年4月

2023年3月

藤田医科大学医療科学部助教

学歴

2015年4月

2018年3月

名古屋大学大学院医学系研究科

2013年4月

2015年3月

名古屋大学大学院医学系研究科

2009年4月

2013年3月

藤田医科大学医療科学部

受賞

12 >

2023年6月

European Renal Association, ERA Congress 2023 Travel Grant

2021年3月

第91回日本衛生学会学術総会若手優秀口演賞

2020年12月

公益財団法人上原記念生命科学財団, 2020年度海外留学助成金ポストドクトラルフェローシップ

2020年3月

公益財団法人金原一郎記念医学医療振興財団, 第34回研究交流助成金助成金

2018年5月

国立大学臨床検査学系博士後期課程優秀賞,最優秀賞

論文

12 3 4 5 >

Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study.

Keisuke Maeda Ryosuke Fujii Hiroya Yamada Eiji Munetsuna Mirai Yamazaki Yoshitaka Ando Genki Mizuno Hiroaki Ishikawa Koji Ohashi Yoshiki Tsuboi Yuji Hattori Yuya Ishihara Nobuyuki Hamajima Shuji Hashimoto Koji Suzuki

Endocrine journal 2024年3月

Thioredoxin-interacting protein (TXNIP) plays an important role in glucose metabolism, and its expression is regulated by DNA methylation (DNAm). Although the association between TXNIP DNAm and type 2 diabetes mellitus has been demonstrated in stu...

Assessment of the renal angina index in patients hospitalized in a cardiac intensive care unit.

Eirin Sakaguchi Hiroyuki Naruse Yuya Ishihara Hidekazu Hattori Akira Yamada Hideki Kawai Takashi Muramatsu Yoshiki Tsuboi Ryosuke Fujii Koji Suzuki Junnichi Ishii Kuniaki Saito Masayoshi Sarai Masanobu Yanase Yukio Ozaki Hideo Izawa

Scientific reports 14(1) 75-75 2024年1月

The renal angina index (RAI) is a validated scoring tool for predicting acute kidney injury (AKI). We investigated the efficacy of the RAI in 2436 heterogeneous patients (mean age, 70 years) treated in cardiac intensive care units (CICUs). The RAI...

Low mitochondrial DNA copy number in peripheral blood mononuclear cells is associated with future mortality risk: a long-term follow-up study from Japan.

Genki Mizuno Hiroya Yamada Yoshiki Tsuboi Eiji Munetsuna Mirai Yamazaki Yoshitaka Ando Itsuki Kageyama Yuki Nouchi Atsushi Teshigawara Yuji Hattori Ryosuke Fujii Hiroaki Ishikawa Shuji Hashimoto Koji Ohashi Nobuyuki Hamajima Koji Suzuki

The journal of nutrition, health & aging 28(1) 100013-100013 2024年1月

OBJECTIVES: The mitochondrial DNA (mtDNA) is unique and circular with multiple copies of the genome. The lower mtDNA copy number (mtDNA-CN) in leukocytes is associated with the risk of all-cause mortality. However, its long-term association is unk...

Serum carotenoid levels are positively associated with DNA methylation of thioredoxin-interacting protein.

Keisuke Maeda Hiroya Yamada Eiji Munetsuna Ryosuke Fujii Mirai Yamazaki Yoshitaka Ando Genki Mizuno Yoshiki Tsuboi Hiroaki Ishikawa Koji Ohashi Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2023年9月

Background: Carotenoids have been reported to exert protective effects against age-related diseases via changes in DNA methylation. Although lower thioredoxin-interacting protein (TXNIP) DNA methylation is associated with age-related diseases, onl...

Integration of methylation quantitative trait loci (mQTL) on dietary intake on DNA methylation levels: an example of n-3 PUFA and ABCA1 gene.

Ryosuke Fujii Yoshitaka Ando Hiroya Yamada Yoshiki Tsuboi Eiji Munetsuna Mirai Yamazaki Genki Mizuno Keisuke Maeda Koji Ohashi Hiroaki Ishikawa Mami Watanabe Nahomi Imaeda Chiho Goto Kenji Wakai Shuji Hashimoto Koji Suzuki

European journal of clinical nutrition 77(9) 881-887 2023年8月

BACKGROUND: Epigenetic studies have reported relationships between dietary nutrient intake and methylation levels. However, genetic variants that may affect DNA methylation (DNAm) pattern, called methylation quantitative loci (mQTL), are usually o...

MISC

Serum levels of miRNA-221 and-222 may be predictive biomarkers for cognitive decline

Yuya Ishihara Hiroya Yamada Eiji Munetuna Chiharu Hagiwara Ryosuke Fujii Mirai Yamazaki Takeshi Hatta Akihiko Iwahara Koji Ohashi Hiroaki Ishikawa Yoshitaka Ando Genki Mizuno Yoshiki Tuboi Koji Suzuki

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY 50 2021年9月