So Masaki#   Rei Yoshimoto#   Daisuke Kaida   Asuka Hata   Takayuki Satoh   Mutsuhito Ohno   Naoyuki Kataoka   
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16(2) 3705-3721 2015年2月 [査読有り]
In eukaryotes, pre-mRNA splicing is an essential step for gene expression. We have been analyzing post-splicing intron turnover steps in higher eukaryotes. Here, we report protein interaction between human Debranching enzyme 1 (hDbr1) and several ...
Rei Yoshimoto   Katsuya Okawa   Minoru Yoshida   Mutsuhito Ohno   Naoyuki Kataoka   
GENES TO CELLS 19(1) 78-87 2014年1月 [査読有り]
To identify the novel factors involved in the postsplicing intron turnover pathway, we carried out immunoprecipitation with known postsplicing factors, hPrp43 and TFIP11. As an interacting factor, we identified C2ORF3 protein by mass spectrometry....
RNA splicing is an important target for basic research of disease mechanisms and for drug discovery. Here, we report a new method for analysis of the in vitro RNA splicing process that produces fluorescence using a reduction-triggered fluorescence...
MOLECULAR CANCER RESEARCH 10(6) 787-799 2012年6月 [査読有り]
The Far UpStream Element (FUSE)-binding protein-interacting repressor (FIR), a c-myc transcriptional suppressor, is alternatively spliced removing the transcriptional repression domain within exon 2 (FIR Delta exon2) in colorectal cancers. SAP155 ...
A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Specialized enzymes add methyl groups to the nitrogens of the amino acid histidine, altering the chemical properties of its imidazole ring and, in turn, the function of the modified (poly)peptide. In this issue of Genes & Development, Shimazu and ...