Acetylcholine is a neuromodulator critical for learning and memory. The cholinesterase inhibitor donepezil increases brain acetylcholine levels and improves Alzheimer's disease (AD)-associated learning disabilities. Acetylcholine activates striata...
Takashi Nakano   Shakila B. Rizwan   David M. A. Myint   Jason Gray   Sean M. Mackay   Paul Harris   Christopher G. Perk   Brian I. Hyland   Ruth Empson   Eng Wui Tan   Keshav M. Dani   John NJ Reynolds   Jeffery R. Wickens   
Pharmaceutics 14(2) 468-468 2022年2月 [査読有り]
Drug delivery systems have the potential to deliver high concentrations of drug to target areas on demand, while elsewhere and at other times encapsulating the drug, to limit unwanted actions. Here we show proof of concept in vivo and ex vivo test...
Neurofeedback (NF) aptitude, which refers to an individual's ability to change brain activity through NF training, has been reported to vary significantly from person to person. The prediction of individual NF aptitudes is critical in clinical app...
Takashi Nakano   Catherine Chin   David Mo Aung Myint   Eng Wui Tan   Peter John Hale   John N. J. Reynolds   Jeff Wickens   Keshav M. Dani   
2014 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO) 2014年
The development of fast and robust chemical delivery systems is important step for nanomedicine. We demonstrate on-demand, sub-second, controlled release of a neuromodulator by applying femtosecond laser pulse trains to robust, liposome structures.