Human observers perceive illusory rotations after the disappearance of circularly repeating patches containing dark-to-light luminance. This afterimage rotation is a very powerful phenomenon, but little is known about the mechanisms underlying it....
Crosstalk between neurons and glia may constitute a significant part of information processing in the brain. We present a novel method of statistically identifying interactions in a neuron-glia network. We attempted to identify neuron-glia interac...
Sho Yagishita   Akiko Hayashi-Takagi   Graham C. R. Ellis-Davies   Hidetoshi Urakubo   Shin Ishii   Haruo Kasai   
SCIENCE 345(6204) 1616-1620 2014年9月 [査読有り]
Animal behaviors are reinforced by subsequent rewards following within a narrow time window. Such reward signals are primarily coded by dopamine, which modulates the synaptic connections of medium spiny neurons in the striatum. The mechanisms of t...
A dendritic spine is a very small structure (similar to 0.1 mu m(3)) of a neuron that processes input timing information. Why are spines so small? Here, we provide functional reasons; the size of spines is optimal for information coding. Spines co...
Ca2+/Calrnodulin-dependent protein kinase II (CaMKII) has been shown to play a major role in establishing memories through complex molecular interactions including phosphorylation of multiple synaptic targets. However, it is still controversial wh...